Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Patent
1998-11-13
2000-06-06
Achutamurthy, Ponnathapu
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
435 6, 530350, 536 231, 536 232, C12N 1512
Patent
active
060717211
ABSTRACT:
The invention provides a human calcium binding protein (hCBP) and polynucleotides which identify and encode hCBP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists The invention also provides methods for diagnosing, treating, or preventing disorders associated with expression of hCBP.
REFERENCES:
Celio, M.R. et al., Guidebook to the Calcium-Binding Proteins, Oxford University Press, Oxford, UK. pp. 15-20 (1996).
Nozaki, M. et al., "Molecular Characterization of the Drosophila Mo25 Gene, Which Is Conserved among Drosophila, Mouse, and Yeast", DNA and Cell Biology 15(6): 505-509 (1996).
Miyamoto, H. et al., "Molecular Cloning of a Novel mRNA Sequence Expressed in Cleavage Stage Mouse Embryos", Mol. Reprod. Dev. 34: 1-7 (1993).
Kissinger, C.R. et al., "Crystal structures of human calcineurin and the human FKBP12-FK506-calcineurin complex", Nature 378(6557): 641-644 (1995).
Wang, M.G. et al., "Calcineurin A alpha (PPP3CA), calcineurin A beta (PPP3CB) and calcineurin B (PPP3R1) are located on human chromosomes 4, 10q21.fwdarw.q22 and 2p16.fwdarw.p15 respectively", Cytogenet. Cell Genet. 72: 236-241 (1996).
Rasmussen, C.D. and Means, A.R., "Calmodulin, cell growth and gene expression", Trends in Neuroscience 12: 433-438 (1989).
Corley Neil C.
Gorgone Gina A.
Guegler Karl J.
Tang Y. Tom
Achutamurthy Ponnathapu
Hutson Richard
Incyte Pharmaceuticals Inc.
Muenzen Colette C.
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