Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Patent
1997-06-27
1998-09-08
Grimes, Eric
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
435 6, 4352523, 43525411, 4353201, 435325, 536 235, 536 2431, C12N 121, C12N 1512, C12N 1563, C12P 2102
Patent
active
058044191
ABSTRACT:
The invention provides a human calcium-binding phosphoprotein (CBPP-1) and polynucleotides which identify and encode CBPP-1. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for treating disorders associated with expression of CBPP-1.
REFERENCES:
patent: 5498533 (1996-03-01), Poovaiah et al.
Celio, M.R., et al., "Introduction to EF-hand calcium-binding proteins," Guidebook to Calcium-binding Proteins, Oxford University Press, Oxford, UK, pp. 15-20 (1996).
Lefort, A., et al., "Cloning and sequencing of a calcium-binding protein regulated by cyclic AMP in the thyroid," The EMBO Journal, 8 (1):111-116 (1989) (GI 876; 877).
Schwaninger, M., et al., "Inhibition of cAMP-responsive Element-mediated Gene Transcription by Cyclosporin A and FK506 after Membrane Depolarization," The Journal of Biological Chemistry, 268(31):23111-23115.
Mulkey, R.M., et al., "An Essential Role for Protein Phosphatases in Hippocampal Long-Term Depression," Science, 261:1051-1055 (1993).
El Housni, H., (GI 1359716 and GI 1359717) GenBank Sequence Database (Accession X97966), National Center for Biotechnology Information, National Library of Medicine, Bethesda, Maryland, 20894 (1997).
Nemoto et al., J. Cell Biol. 123:963-976, 1993.
Bandman Olga
Corley Neil C.
Shah Purvi
Billings Lucy J.
Grimes Eric
Incyte Pharmaceuticles, Inc.
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