Calcium-antagonistic composition

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Recombinant or stably-transformed bacterium encoding one or...

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546 21, 548113, A01N 5728, C07F 928, C07D27766, C07D41702

Patent

active

042320100

ABSTRACT:
A phosphonic acid ester of the formula: ##STR1## and R is a lower alkyl, exhibits a calcium-antagonistic activity. Pharmaceutical compositions containing the same are useful in prophylaxis and treatment of ischemic heart diseases such as angina pectoris, myocardial, infarction, etc. and hypertension.

REFERENCES:
patent: 3897442 (1975-07-01), Edwards
Arzneimittel-Forschung, 22, p. 22 (1972), (I).
Arzneimittel-Forschung, 22, p. 1 (1972), (II).
Arzneimittel-Forschung, 21, p. 1338 (1971).
Arzneimittel-Forschung, 27, p. 878 (1977).
Arzneimittel-Forschung, 20, p. 1310 (1970).

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