Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1986-06-17
1988-02-02
Jiles, Henry R.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514333, 546270, 546256, 546321, C07D491056, C07D21190, A61K 31455
Patent
active
047229314
ABSTRACT:
The invention concerns a compound of the formula ##STR1## and salts thereof resulting from addition with pharmaceutically acceptable mineral or organic acid, wherein R is an alkylenedioxy group substituted at the 2',3'-position, and R.sub.1 and R.sub.2 are selected from the group consisting of a linear or branched alkyl having 1-4 carbon atoms, a methoxyethyl, or a 2-pyridyl methyl group. The compounds of the present invention are useful in relaxing cardiac or smooth muscle.
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Bossert, F., H. Meyer, and E. Wehinger, 4-Aryldihydropyridines, a New Class of Highly Active Calcium Antagonists Angew, Chem. Int. E.D. Engl. 20 (1981) 762-769.
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Galiano Ramos Joaquin A.
Verde Casanova Maria J.
Bjorkman Dale A.
Jiles Henry R.
Laboratorios Delagrange
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