Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1989-08-22
1991-07-30
Waddell, Frederick E.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514 23, 514438, 514471, 514579, 514654, 514655, 514659, A61K 3144, A61K 3170, A61K 3138, A61K 3134, A61K 3116, A61K 31135, A61K 3113
Patent
active
050360817
ABSTRACT:
Alpha-glucosidase inhibitor is provided as a promoter of calcium absorption in mammals. The examples of the inhibitor are shown by the formula; ##STR1## wherein A stands for a C.sub.1 -C.sub.10 acyclic hydrocarbon group which may be substituted by hydroxyl, phenoxy, thienyl, furyl, pyridyl, cyclohexyl or phenyl group which itself may be further substituted, a C.sub.5 -C.sub.6 cyclic hydrocarbon group which may be substituted by hydroxyl, hydroxymethyl, methyl or amino group, or a sugar residue.
There is also provided a calcium preparation which contains an .alpha.-glucosidase inhibitor and a calcium source.
REFERENCES:
patent: 4486602 (1984-12-01), Horii et al.
patent: 4701559 (1987-10-01), Horii et al.
patent: 4777294 (1988-10-01), Horii et al.
E. Truscheit, et al., "Chemistry and Biochemistry of Microbial a-Glucosidase Inhibitors", Angewandte Chemie International Edition in English, vol. 20 (9), pp. 744-761 (1981).
Matsuo Takao
Odaka Hiroyuki
Suzuki Tsuyoshi
Tsuda Masao
Henley III Raymond J.
Takeda Chemical Industries Ltd.
Waddell Frederick E.
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