Calcitonin gene related peptide analogs with C-terminal D-amino

Details Calcitonin gene related peptide analogs with C-terminal D-amino Calcitonin gene related peptide analogs with C-terminal D-amino

1985-12-23

1987-08-18

Phillips, Delbert R.

Chemistry: natural resins or derivatives; peptides or proteins;

Peptides of 3 to 100 amino acid residues

25 or more amino acid residues in defined sequence

C07K 710

Patent

active

046878394

ABSTRACT:
New calcitonin gene related peptide analogs (CGRP) are disclosed which have biological activity of the same type as known calcitonin gene related peptides and which have a D-amino acid substituent in at least one of the positions 36 and 37 instead of the natural L-amino acids.

REFERENCES:
patent: 3929758 (1975-12-01), Hughes et al.
patent: 4530838 (1985-07-01), Evans et al.
patent: 4549986 (1985-10-01), Evans et al.

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