Calcitonin gene related peptide analogs with amino acid subdstit

Details Calcitonin gene related peptide analogs with amino acid subdstit Calcitonin gene related peptide analogs with amino acid subdstit

1985-12-23

1987-09-29

Phillips, Delbert R.

Chemistry: natural resins or derivatives; peptides or proteins;

Peptides of 3 to 100 amino acid residues

25 or more amino acid residues in defined sequence

C07K 710

Patent

active

046970029

ABSTRACT:
New calcitonin gene related peptide analogs (CGRP) are disclosed which have biological activity of the same type as known calcitonin gene related peptides and which have an amino acid substituent at position 36 or the penultimate position instead of the naturally occurring amino acid--Ala.

REFERENCES:
patent: 3929758 (1975-12-01), Hughes et al.
patent: 4530838 (1985-07-01), Evans et al.
patent: 4549986 (1985-10-01), Evans et al.

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