Calcitonin analogs with amino acid substituents at position 31

Details Calcitonin analogs with amino acid substituents at position 31 Calcitonin analogs with amino acid substituents at position 31

1985-10-01

1987-02-17

Phillips, Delbert R.

Chemistry: natural resins or derivatives; peptides or proteins;

Peptides of 3 to 100 amino acid residues

Calcitonin; related peptides

514808, C07K 736, A61K 3724

Patent

active

046440542

ABSTRACT:
New polypeptides are disclosed which have biological activity of the same degree as known calcitonins and which have amino acid substituents in position 31 instead of the naturally occuring amino acids--Thr, Ala, Val.

REFERENCES:
patent: 3929758 (1975-12-01), Hughes et al.
Rittel et al., Experientia, 15(2), 273-275 (1975).
Guttmann, Calcitonin 1980, Proceedings of an International Symposium held in Milan, Oct. 15-17, 1980.

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