Bleaching and dyeing; fluid treatment and chemical modification – Treatment of hides – skins – feathers and animal tissues – Internal tissues
Patent
1988-04-01
1992-03-10
Willis, Jr., Prince
Bleaching and dyeing; fluid treatment and chemical modification
Treatment of hides, skins, feathers and animal tissues
Internal tissues
8 9429, 623 1, 623 2, 623 11, 623 22, A61L 1700, A63B 5102
Patent
active
050946617
ABSTRACT:
Bioprosthetic materials, either natural or synthetic, are treated with trivalent aluminum cations to prevent in vivo calcification. Such bioprosthetic materials include porcine aortic valve leaflets, bovine pericardium, aortic homografts, biocompatible elastomers, and the like which are intended for invasive, or in-dwelling use in a human or animal body. Simple incubation of the natural bioprosthetic materials in an aluminum ion-containing solution, such as aqueous AlCl.sub.3, prior to implantation has been found to inhibit calcification of the biomaterial over a prolonged period and to do so without adverse side effects. Incorporation of an aluminum-containing compound into the formulation for polymers, such as polyurethane, has also been found to inhibit calcification with no adverse side effects.
REFERENCES:
patent: 713046 (1902-11-01), Amend
patent: 725648 (1903-04-01), Amend
patent: 2750251 (1956-06-01), Bloch et al.
patent: 3650141 (1971-02-01), Kurilla et al.
patent: 3922356 (1975-11-01), Cohly
patent: 4097234 (1978-06-01), Sohde et al.
patent: 4481009 (1984-11-01), Nashef
patent: 4597960 (1986-07-01), Cohen
patent: 4753652 (1988-06-01), Langer
patent: 4770665 (1988-09-01), Nashef
Levy Robert J.
Sintov Amnon
McNally John F.
The University of Michigan
Willis Jr. Prince
LandOfFree
Calcification-resistant materials and methods of making same thr does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Calcification-resistant materials and methods of making same thr, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Calcification-resistant materials and methods of making same thr will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2282288