Calcification mitigation of bioprosthetic implants

Details Calcification mitigation of bioprosthetic implants Calcification mitigation of bioprosthetic implants

1989-04-18

1991-03-26

Cannon, Alan W.

Prosthesis (i.e., artificial body members), parts thereof, or ai

Heart valve

Having rigid or semirigid pivoting occluder

623 11, 8 9428, 8 9419R, A61F 224

Patent

active

050025660

ABSTRACT:
Calcification resistant bioprosthetic implants are made from tanned biological materials, such as porcine heart valves, bovine pericardium, human dura mater or the like, which has been impregnated with a calcification-mitigating effective amount of a ferric and/or stannic salt. The impregnated biological materials and processes are particularly advantageous for the preparation of bioprosthetic heart valves. These implants have been found to be highly resistant to calcification in vivo.

REFERENCES:
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patent: 4097234 (1978-06-01), Sohde et al.
patent: 4323358 (1982-04-01), Lentz et al.
patent: 4378224 (1983-03-01), Nimni et al.
patent: 4481009 (1984-11-01), Nashef
patent: 4553974 (1985-11-01), Dewanjee
patent: 4648881 (1987-03-01), Carpentier et al.

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