Liquid purification or separation – With means to add treating material – Chromatography
Reexamination Certificate
2007-04-24
2007-04-24
Therkorn, Ernest G. (Department: 1723)
Liquid purification or separation
With means to add treating material
Chromatography
C210S198300, C210S656000
Reexamination Certificate
active
10477977
ABSTRACT:
The present invention discloses a new and improved kind of chromatographic cake and its manufacturing methods and applications. The objective of this invention is to provide an improved chromatographic apparatus and methods for manufacturing such an apparatus, whereby the separation and simultaneous renaturation and purification of biopolymers can be efficiently performed with excellent results. The chromatographic cakes of this invention generally comprise a chromatographic packing cake with a mobile phase inlet and a mobile phase outlet, together with a chromatographic packing packed into an inner cavity region of the chromatographic packing cake. The ratio of the thickness to the diameter of the inner cavity region of the chromatographic packing cake is less than or equal to 1. A method of manufacturing such chromatographic cakes generally comprises the steps of: 1) Manufacturing the chromatographic packing cake, wherein the chromatographic packing cake includes combined upper and lower clamp plates having, respectively, a mobile phase inlet or outlet, and a cake body with at least one lateral hole or aperture; wherein the ratio of the thickness to the diametral dimension of the inner cavity of the chromatographic packing cake is smaller than or equal to 1; and, 2) adding chromatographic packing in whole or at least in part using the lateral hole(s) of the chromatographic packing cake to fill the inner cavity of the chromatographic-packing cake with a suitable packing material.
REFERENCES:
patent: 3780866 (1973-12-01), Ek et al.
patent: 4497711 (1985-02-01), Shepherd
patent: 4557830 (1985-12-01), Onitsuka et al.
patent: 4582608 (1986-04-01), Ritacco
patent: 4710289 (1987-12-01), Wermuth et al.
patent: 4722786 (1988-02-01), Weaver
patent: 4732687 (1988-03-01), Muller et al.
patent: 4737284 (1988-04-01), Hauke et al.
patent: 4737292 (1988-04-01), Ritacco et al.
patent: 4806238 (1989-02-01), Sattler et al.
patent: 4865729 (1989-09-01), Saxena et al.
patent: 5089125 (1992-02-01), Hart et al.
patent: 5141635 (1992-08-01), LePlang et al.
patent: 5238556 (1993-08-01), Shirkhan
patent: 5324426 (1994-06-01), Joseph et al.
patent: 5589062 (1996-12-01), Rice
patent: 5667676 (1997-09-01), Alaska
patent: 5693223 (1997-12-01), Yamada et al.
patent: 5863428 (1999-01-01), Ma et al.
patent: 6001253 (1999-12-01), Conroy et al.
patent: 6080616 (2000-06-01), Kim
patent: 2004/0140252 (2004-07-01), Gebauer
patent: 1 074 835 (2000-07-01), None
patent: 7-301626 (1995-11-01), None
patent: 2 060 498 (1996-05-01), None
Machine Translation of Japan Patent No. 7-301626.
Geng Xindu
Zhang Yangjun
Andover-IP-Law
Northwest University
Silverstein David
Therkorn Ernest G.
LandOfFree
Caky chromatographic column and the method for producing it... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Caky chromatographic column and the method for producing it..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Caky chromatographic column and the method for producing it... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3722939