Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for... – Transferase other than ribonuclease
Reexamination Certificate
2006-07-18
2006-07-18
Witz, Jean C. (Department: 1651)
Chemistry: molecular biology and microbiology
Enzyme , proenzyme; compositions thereof; process for...
Transferase other than ribonuclease
C435S267000, C514S279000, C514S283000
Reexamination Certificate
active
07078209
ABSTRACT:
The present invention relates to compounds useful as inhibitors of CAK, compositions thereof. The present invention also relates to methods using the compositions for treating CAK-mediated diseases, such as fungal infections.
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Pauls, H., et al., “Umsetzungen mit CH-aciden Verbindungen and Übergang in Indolizine,”Chemische Berichten, 10:1294-1303 (1997).
Mezentseva, M.V., et al., “Synthesis and Antitumor Activity of Pyrrolo [3,2-d] Pyrimidines,”Pharmaceutical Chemistry Journal, 25:858-864 (1991).
Sato, K., et al., “Studies of heterocyclic compound. XI. The synthesis of oxazolo [3,2-b] pyridazinium perchlorates and their reactions with some C-nucleophiles”,Chemical abstract, 87(13), abstract No. 102255a, (1977).
Abd el Salam, O., “Synthesis of some new pyrimido [5,4-a] indolizines,”Monatshefte für Chemie, 131:959-965 (Sep. 2000).
Ledford Brian
Moody Cameron Stuver
Mullican Michael
Namchuk Mark
Brown Karen E.
Hanley Susan
Vertex Pharmaceuticals Incorporated
Vertex Pharmaceuticals Incorporated
Witz Jean C.
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