Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Patent
1995-06-07
1997-08-12
Scheiner, Toni R.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
435 72, 5303879, 53038873, 53038875, G01N 3353, G01N 33567, C07K 1600, C12P 2108
Patent
active
056564384
ABSTRACT:
CAIP polypeptide, nucleic acids, antibodies thereto and uses thereof.
REFERENCES:
patent: 5525503 (1996-06-01), Rudd et al.
Abraham, K.M. et al. "Delayed Thymocyte Development Induced by Augmented Expression of p56.sup.lck " J. Exp. Med. 173:1421-1432 (Jun. 1991).
Bartel, P.L. et al. "Using the two-hybrid system to detect protein-protein interactions" in Cellular Interaction in Development: A Practical Approach, D.A. Hartley, ed. (Oxford: Oxford University Press, 1993):153-179.
Bell, G.M. et al. "The SH3 Domain of p56.sup.lck Binds to Proline-rich Sequences in the Cytoplasmic Domain of CD2" J. Exp. Med. 183:169-178 (Jan. 1996).
Hall, J.L. et al. "Identification of Two Human .beta.-Tubulin Isotypes" Mol. Cell. Biol. 3(5):854-862 (May 1983).
Ramos-Morales, F. et al. "P56.sup.lck : A Transducing Protein That Binds to SH2 Containing Proteins and to Phosphotyrosine Containing Proteins" Cell. Mol. Biol. 40(5):695-700 (1994).
Ramos-Morales, F. et al. "Vav binds to several SH2/SH3 containing proteins in activated lymphocytes" Oncogene 9(7):1917-1923 (1994).
Reeck, G.R. et al. "Homology in Proteins and Nucleic Acids: A Terminology Muddle and a Way out of It" Cell 50:667 (27 Aug. 1987).
Bierer et al., "Partial deletions of the cytoplasmic domain of CD2 result in a partial defect in signal transduction," Journal of Immunology, vol. 144, No. 3, 785-789 (1990).
Bromberg, "The Biology of CD2: Adhesion, Transmembrane Signal, and Regulatory Receptor of Immunity," Journal of Surgical Research, vol. 54, 258-267 (1993).
Carmo et al., "Physical association of the cytoplasmic domain of CD2 with the tyrosine kinases p56.sup.lck and p 59.sup.fyn," Eur. J. Immunol., vol. 23, 2196-2201 (1993).
Carrera et al., "CD2 is involved in regulating cyclic AMP levels in T cells," Eur. J. Immunol., vol. 18, 961-964 (1988).
Chang et al., "Dissection of the human CD2 intracellular domain," J. Exp. Med., vol. 169, 2073-2083 (1989).
Dayhoff et al., "A Model of Evolutionary Change in Proteins," Atlas of Protein Sequence and Structure, Chp. 22, 345-352 (1978).
Donovan, et al., "Restoration of CD2-Mediated Signaling by a Chimeric Membrane Protein Including the Cytoplasmic Sequence of CD45," Human Immunology, vol. 40, 123-130 (1994).
Franco et al., "Regulation of CD2-Mediated Human T Cell Activation: Anti-CD8 Monoclonal Antibodies Inhibit CD2-Mediated Rise in Intracellular Calcium," Cellular Immunology, vol. 152, 162-175 (1993).
Gassmann et al., "Identification of a signaling complex involving CD2, .zeta. chain and p59.sup.tyn in T lymphocytes," Eur. J. Immunol., vol. 24, 139-144 (1994).
Hahn, et al., "A distinct cytoplasmic domain of CD2 regulates ligand avidity and T-cell responsiveness to antigen," Proc. Natl. Acad. Sci. USA., vol. 89, 7179-7183 (1992).
Hahn et al., "Signal Transduction Pathways Involved in T Cell Receptor-Induced Regulation of CD2 Avidity for CD58.sup.1," Journal of Immunology, vol. 150, No. 7, 2607-2619 (1993).
He et al., "A Role in Transmembrane Signaling for the Cytoplasmic Domain of the CD2 T Lymphocyte Surface Antigen," Cell, vol. 54, 979-984 (1988).
Hein, "Unified Approach to Alignment and Phylogenies," Methods in Enzymology, vol. 183, 626-645 (1990).
Koch et al., "SH2 and SH3 Domains: Elements That Control Interactions of Cytoplasmic Signaling Proteins," Science, vol. 252, 668-674 (1991).
Kozarsky et al., "An Anti-CD2 Monoclonal Antibody That Both Inhibits and Stimulates T Cell Activation Recognizes a Subregion of CD2 Distinct from Known Ligand-Binding Sites," Cellular Immunology, vol. 150, 235-246 (1993).
Moingeon et al., "The Structural Biology of CD2," Immunological Reviews, No. 111, 111-144 (1989).
Offringa and Bierer, "Association of CD2 with Tubulin," Journal of Biological Chemistry, vol. 268, No. 7, 4979-4988 (1993).
Saitou and Nei, "The Neighbor-joining Method: A New Method for Reconstructing Phylogenetic Trees," Mol. Biol. Evol., vol. 4(4), 406-425 (1987).
Sato et al., "Cytoplasmic Membrane-Associated Protein (CAP) Isolated from Streptococcus pyogenes: As a New Bacterial Superantigen," Microbiol. Immunol., vol. 38(2), 139-147 (1994).
Schlessinger, "SH2/SH3 signaling proteins: Oncogenes and cell proliferation," Current Opinion in Genetics and Development, vol. 4, 25-30 (1994).
Schwartz and Dayhoff, "Matrices for Detecting Distant Relationships," in Atlas of Protein Sequence and Structure, Chp. 23, 353-357 (1978).
Suthanthiran, "Transmembrane signalling via the T cell antigen receptor heterodimer and the CD2 antigen," Transplantation, vol. 47, No. 2, 348-351 (1989).
Wilbur et al., "Rapid similarity searches of nucleic acid and protein data banks," Proc. Natl. Acad. Sci. USA, vol. 80, 726-730 (1983).
Biogen Inc.
Eyler Yvonne
Myers Louis
Scheiner Toni R.
LandOfFree
CAIP-like gene family does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with CAIP-like gene family, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and CAIP-like gene family will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-159293