Caenorhabditis elegans chemosensory bioassay for seven...

Details Caenorhabditis elegans chemosensory bioassay for seven... Caenorhabditis elegans chemosensory bioassay for seven...

2005-06-21

2005-06-21

Paras, Jr., Peter (Department: 1632)

Multicellular living organisms and unmodified parts thereof and

Method of using a transgenic nonhuman animal in an in vivo...

C800S013000

Reexamination Certificate

active

06909029

ABSTRACT:
This invention relates to methods for producing a transgenicC. elegansthat expresses a human 7TMR pan-neuronally, such that said transgenicC. elegansexhibits a known phenotype. These transgenicC. eleganscan be used in a variety of ways, including, but not limited to: (1) screening and identifying substances that bind to and activate particular human 7TMRs; (2) screening for substances that antagonize human 7TMR activation; (3) identifying human 7TMRs that may respond to particular substances; and (4) evaluating the specificity and efficacy of substances on human 7TMR activation.

REFERENCES:
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