C7 tricyclic taxanes

Organic compounds -- part of the class 532-570 series – Organic compounds – Carboxylic acid esters

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549510, 549511, C07C27110, C07D30514

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active

059945761

ABSTRACT:
Taxane derivatives having alternative C7 substituents.

REFERENCES:
patent: 4814470 (1989-03-01), Colin et al.
patent: 4857653 (1989-08-01), Colin et al.
patent: 4876399 (1989-10-01), Holton et al.
patent: 4924011 (1990-05-01), Denis et al.
patent: 4924012 (1990-05-01), Colin et al.
patent: 4960790 (1990-10-01), Stella et al.
patent: 5015744 (1991-05-01), Holton
patent: 5136060 (1992-08-01), Holton
patent: 5175315 (1992-12-01), Holton
patent: 5227400 (1993-07-01), Holton et al.
patent: 5229526 (1993-07-01), Holton
patent: 5243045 (1993-09-01), Holton et al.
patent: 5248796 (1993-09-01), Chen et al.
patent: 5250683 (1993-10-01), Holton et al.
patent: 5254580 (1993-10-01), Chen et al.
patent: 5254703 (1993-10-01), Holton
patent: 5264591 (1993-11-01), Bombardelli et al.
patent: 5272171 (1993-12-01), Ueda et al.
patent: 5274124 (1993-12-01), Holton
patent: 5283253 (1994-02-01), Holton et al.
patent: 5284864 (1994-02-01), Holton et al.
patent: 5284865 (1994-02-01), Holton et al.
patent: 5294637 (1994-03-01), Chen et al.
patent: 5296506 (1994-03-01), Kingston et al.
patent: 5336785 (1994-08-01), Holton
patent: 5338872 (1994-08-01), Holton et al.
patent: 5350866 (1994-09-01), Holton et al.
patent: 5352806 (1994-10-01), Gunawardana et al.
patent: 5384399 (1995-01-01), Holton
patent: 5399726 (1995-03-01), Holton et al.
patent: 5405972 (1995-04-01), Holton et al.
patent: 5430160 (1995-07-01), Holton
patent: 5440056 (1995-08-01), Klein et al.
patent: 5466834 (1995-11-01), Holton
patent: 5478854 (1995-12-01), Farina et al.
patent: 5489601 (1996-02-01), Holton et al.
patent: 5530020 (1996-06-01), Gunawardana et al.
patent: 5532363 (1996-07-01), Holton
patent: 5539103 (1996-07-01), Holton
patent: 5594157 (1997-01-01), Gunawardana et al.
patent: 5616740 (1997-04-01), Klein et al.
patent: 5721268 (1998-02-01), Holton et al.
S. Borman, "New Family of Taxol, Taxotere Analogs Developed" Science & Technology, Chem. & Eng. News, pp. 26-27, (Apr. 1993).
V. Farina et al., "The Chemistry of Taxanes: Unexpected Rearrangement Of Baccatin III During Chemoselective Debenzoylation with Bu.sub.3 SnOMe/LiCl", Tetrahedron Letters, vol. 33, No. 28, pp. 3979-3982 (1992).
D. Kingston et al., "The Chemistry of Taxol, A Clinically Useful Anticancer Agent", Journal of Natural Products, vol. 53, No. 1 (1990) pp. 1-12.
Kingston et al., "Progress in the Chemistry of Organic Natural Products 61", Springer-Verlag, Wien New York 1993.
N. Magri et al., "Modified Taxols, 4. Synthesis and Biological Activity of Taxols Modified in the Side Chain", J. of Natural Products, vol. 51, No. 2 (1988) pp. 298-306.
W. Mellado et al., "Preparation and Biological Activity of Taxol Acetates", Biochem. & Biophys. Research Communications, vol. 124, No. 2 (1984) pp. 329-336.
Ojima et al., "New and Efficient Approaches to the Semisynthesis of Taxol and Its C-13 Side Chain Analogs by Means of .beta.-Lactam Synthon Method", Tetrahedron Letters, vol. 48, No. 34, pp. 6985-7012 (1992).
G. Samaranayake et al., "Modified Taxols, 5. Reaction of Taxol With Electrophilic Reagents and Preparation of a Rearranged Taxol Derivative with Tubulin Assembly Activity", J. Org. Chem., vol. 56 (1991) pp. 5114-5119.

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