C10 heterosubstituted acetate taxane compositions

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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C549S060000, C549S471000, C514S444000

Reexamination Certificate

active

11068166

ABSTRACT:
Compositions comprising a taxane having a heterosubstituted acetate substituent at C(10), a hydroxy substituent at C(7), and a range of C(2), C(9), C(14), and side chain substituents.

REFERENCES:
patent: 4960790 (1990-10-01), Stella et al.
patent: 5175315 (1992-12-01), Holton
patent: 5227400 (1993-07-01), Holton et al.
patent: 5243045 (1993-09-01), Holton et al.
patent: 5283253 (1994-02-01), Holton et al.
patent: 5350866 (1994-09-01), Holton et al.
patent: 5430160 (1995-07-01), Holton
patent: 5556877 (1996-09-01), Bouchard et al.
patent: 5556878 (1996-09-01), Kelly et al.
patent: 5567614 (1996-10-01), Patel et al.
patent: 5614645 (1997-03-01), Kingston et al.
patent: 5714513 (1998-02-01), Holton et al.
patent: 5721268 (1998-02-01), Holton et al.
patent: 5756536 (1998-05-01), Chen et al.
patent: 5767297 (1998-06-01), Mandai et al.
patent: 5780653 (1998-07-01), Tao et al.
patent: 5811452 (1998-09-01), Ojima et al.
patent: 5879929 (1999-03-01), Patel
patent: 5889043 (1999-03-01), Bouchard et al.
patent: 5912264 (1999-06-01), Wittman et al.
patent: 5939561 (1999-08-01), Bourzat et al.
patent: 6664275 (2003-12-01), Holton
patent: 6872837 (2005-03-01), Holton
patent: 0 558 959 (1993-09-01), None
patent: 0 629 701 (1994-12-01), None
patent: 0 687 259 (1995-12-01), None
patent: 0 882 732 (1998-12-01), None
patent: WO 93/18018 (1993-09-01), None
patent: WO 94/20484 (1994-09-01), None
patent: WO 95/11241 (1995-04-01), None
patent: WO 96/13495 (1996-05-01), None
patent: WO 97/09979 (1997-03-01), None
patent: WO 97/16200 (1997-05-01), None
patent: WO 97/42181 (1997-11-01), None
patent: WO 98/02426 (1998-01-01), None
patent: WO 99/09021 (1999-02-01), None
patent: WO 9904761 (1999-02-01), None
patent: WO 01/57013 (2001-08-01), None
Gueritte-Voegelein et al. “Relationships between the Structure of Taxol Analogues and Their Antimitotic Activity” Journal of Medicinal Chemistry, vol. 34, No. 3 (1991) pp. 992-998.
Kant et al. “A Chemoselective Approach to Functionalize the C-10 Position of 10-Deacetylbaccatin III. Synthesis and Biological Properties of Novel C-10 Taxol Analogues” Tetrahedron Letters, vol. 35, No. 30 (1994) pp. 5543-5546.
Kingston et al. “The Chemistry of Taxol, A Clinically Useful Anticancer Agent” J. of Natural Products, vol. 53, No. 1 (1990) pp. 1-12.
Mellado et al. “Preparation and Biological Activity of Taxol Acetates” Biochemical and Biophysical Research Communications vol. 124, No. 2 (1984) pp. 329-336.
Pulicani et al. “Direct Access to 2-Debenzoyl Taxoids by Electrochemistry, Synthesis of 2-Modified Docetaxel Analogs” Tetrahedron Letters, vol. 35 No. 52 (1994) pp. 9717-9720.
RAO et al. “Synthesis and Evaluation of Some 10-Mono- and 2',10-Diesters of 10-Deacetylpaclitaxel” Journal of Medicinal Chemistry, vol. 38, No. 17 (1995) pp. 3411-3414.
Samaranayake et al. “Modified TAxols. 5. Reaction of Taxol with Electrophilic Reagents and Preparation of a Rearranged Taxol Derivative with Tubulin Assembly Activity” J. Org. Chem., vol. 56, No. 17 (1991) pp. 5114-5119.
Straubinger et al. “Pharmacology and Antitumor Effect of Novel Placlitaxel Formulations” Chapter 8, Edited by G. Georg et al., Taxane Anticancer Agents, Basic Science and Current Status, ACS Symposium Series 583, 207th National Meeting of the American Chemical Society, San Diego, CA (1994) pp. 111-123.
Suffness “Chapter 32. Taxol: From Discovery to Therapeutic Use” Annual Reports in Medicinal Chemistry, vol. 28 (1993) pp. 305-314.
International Search Report for analogous PCT Application No. PCT/US01/03553 dated Jun. 11, 2001.
Journal of Tianjin University, (2000), pp. 51-55, vol. 33:1.

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