C-terminal peptide sequencing method

Details C-terminal peptide sequencing method C-terminal peptide sequencing method

1991-10-18

1993-07-13

Housel, James C.

Chemistry: analytical and immunological testing

Peptide, protein or amino acid

Amino acid or sequencing procedure

436175, 436178, 530345, 530408, 530409, 530810, G01N 3368

Patent

active

052273091

ABSTRACT:
A method for the C-terminal sequencing of a peptide in which an alkyl or aryl tin isothiocyanate coupling reagent is used to form a thiohydantoin derivative. Free halogen producing activating agents, such as 2-halo-1-methyl pyridinium salts, may be used as an activating agent for the coupling reagent.

REFERENCES:
patent: 5051368 (1991-09-01), Boyd et al.

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