C-terminal modified (n-substituted)-2-indolyl dipeptides as inhi

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514419, 514385, 548492, 548493, 5483121, A61K 3140, A61K 31405, C07D20914, C07D20942

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active

058695192

ABSTRACT:
This invention is directed to novel (N-substituted)indole ICE-inhibitor compounds. The invention is also directed to pharmaceutical compositions of such indole compounds, plus the use of such compositions in the treatment of patients suffering inflammatory, autoimmune and neurodegenerative diseases, for the prevention of ischemic injury, and for the preservation of organs that are to undergo a transplantation procedure.

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