Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai
Patent
1995-03-30
1997-08-19
Kight, John
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Carbohydrate doai
514 47, 536 2624, A61K 3170, C07H 2300
Patent
active
056588909
ABSTRACT:
This invention provides a compound having the structure: ##STR1## wherein each R.sub.1, R.sub.2, R.sub.3, and R.sub.4 is independently fluorine, OH or H; Z is O, CH.sub.2 or CF.sub.2 ; each Y is independently OH or F; X.sub.7 is N or CH, X.sub.8 is NH, S or Se; and W is C or N, wherein when W is C, the dashed line (---) represents a double bond and X.sub.9 is N or CH, and wherein when W is N, the dashed line (---) represents a single bond and X.sub.9 is S or Se, or the dashed line (---) represents a double bond and X.sub.9 is N or CH.
This invention also provides a pharmaceutical composition comprising the compounds and methods of treating a mammal having an inosine monophosphate dehydrogenase associated disorder.
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Pankiewicz Krysztof W.
Watanabe Kyoichi A.
Zatorski Andrzej
Crane L. Eric
Kight John
Sloan-Kettering Institute for Cancer Research
White John P.
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