C-myb transfected T98G cells which produce GM-CSF and stem cell

Details C-myb transfected T98G cells which produce GM-CSF and stem cell C-myb transfected T98G cells which produce GM-CSF and stem cell

1993-07-29

1994-11-08

Hill, Jr., Robert J.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

435 694, 4352402, C12N 522, C12N 1519

Patent

active

053626311

ABSTRACT:
A c-myb transfected cell line capable of producing a selected growth factor is provided. In a preferred embodiment, human glioblastoma cells are co-transfected with a first plasmid containing human c-myb DNA and second plasmid containing the gene encoding hygromycin resistance. Methods of producing selected growth factors employing cell line are also provided.

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Majello, B., Kenyon, L. C. and Dalla-Favera, R. (1986) Huan c-myb Proto-oncogene: Nucleotide Sequence of cDNA and Organization of Genomic Locus, Proc. Natl. Acad. Sci., USA, 83:9616.
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