Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2007-05-24
2011-11-29
Bernhardt, Emily (Department: 1624)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C546S153000, C544S119000, C544S287000, C544S363000, C544S128000, C514S234500, C514S235200, C514S252170, C514S253070, C514S266200, C514S266220, C514S266300
Reexamination Certificate
active
08067436
ABSTRACT:
The present invention provides compounds for modulating protein kinase enzymatic activity for modulating cellular activities such as proliferation, differentiation, programmed cell death, migration and chemoinvasion. More specifically, the invention provides quinazolines and quinolines which inhibit, regulate, and/or modulate kinase receptor, particularly c-Met, KDF, c-Kit, flt-3 and flt-4, signal transduction pathways related to the changes in cellular activities as mentioned above, compositions which contain these compounds, and methods of using them to treat kinase-dependent diseases and conditions. The present invention also provides methods for making compounds as mentioned above, and compositions which contain these compounds.
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Altomare et a
Bannen Lynne Canne
Chan Diva Sze-Ming
Chen Jeff
Dalrymple Lisa Esther
Forsyth Timothy Patrick
Bernhardt Emily
Berven Heidi M.
Exelixis Inc.
Honigman Miller Schwartz & Cohn
O'Brien Jonathan P.
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