C-glycoside derivatives and salts thereof

Details C-glycoside derivatives and salts thereof C-glycoside derivatives and salts thereof

2007-04-10

2007-04-10

Crane, L. E. (Department: 1623)

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

C536S029200, C514S023000

Reexamination Certificate

active

10541615

ABSTRACT:
The present invention provides C-glycoside derivatives and salts thereof, wherein B ring is bonded to A ring via —X— and A ring is directly bonded to the glucose residue, and it is usable as a Na+-glucose cotransporter inhibitor, especially for a therapeutic and/or preventive agent for diabetes such as insulin-dependent diabetes (type 1 diabetes) and insulin-independent diabetes (type 2 diabetes), as well as diabetes related diseases such as an insulin-resistant diseases and obesity.

REFERENCES:
patent: 6617313 (2003-09-01), Maurya et al.
patent: 2001/0041674 (2001-11-01), Tomiyama et al.
patent: 2005/0032711 (2005-02-01), Patel et al.
patent: 2005/0032712 (2005-02-01), Urbanski
patent: 2005/0037980 (2005-02-01), Rybczynski et al.
patent: 2005/0037981 (2005-02-01), Beavers et al.
patent: 2005/0124555 (2005-06-01), Tomiyama et al.
patent: 2005/0233988 (2005-10-01), Nomura et al.
patent: 6-199695 (1994-07-01), None
patent: 2001-288178 (2001-10-01), None
patent: WO 98/31697 (1998-07-01), None
patent: WO 01/27128 (2001-04-01), None
patent: WO 03/082887 (2003-10-01), None
patent: WO 03/087093 (2003-10-01), None
patent: WO 03/094928 (2003-11-01), None
patent: WO 2004/013118 (2004-02-01), None
patent: WO 2004/080990 (2004-09-01), None
patent: WO 2005/012326 (2005-10-01), None
patent: WO 2006/011502 (2006-02-01), None
Todoulou, et al., “Synthesis and antiviral activity of some new 1H-1,2,4-triazole derivatives”,European Journal of Medicinal Chemistry, 1994, pp. 611-620, vol. 29, No. 7-8.
Buchanan, et al., “Synthesis of C-Glycosyltetrazoles Related to 3-Deoxy-D-arabino-heptulosonic Acid 7-Phosphate (DAHP); Potential Inhibitors of Early Steps in the Shikimate Pathway”,Journal of the Chemical Society, Oct. 21, 1992, pp. 2593-2601, No. 20.
Varma, et al., “Inhibition of Lens Aldose Reductase by Flavonoids—Their Possible Role in the Prevention of Diabetic Cataracts”,Biochemical Pharmacology, Nov. 15, 1976, pp. 2505-2513, vol. 25, No. 22.
Andrade-Cetto, et al., “Hypoglycemic effect ofCecropia obtusifoliaon streptozotocin diabetic rats”,Journal of Ethno-Pharmacology, Dec. 2001, pp. 145-149, vol. 78, Nos. 2-3.
Shen, et al., “Hypoglycemic Effect of the Combined Use of Puerarin and Aspirin in Mice”,Acta Pharmaccutica Sinica, 1985, pp. 863-865.

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