C. elegans gro-1 gene

Chemistry: molecular biology and microbiology – Vector – per se

Reexamination Certificate

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C435S325000, C435S252300, C435S254110, C536S023500, C536S024500

Reexamination Certificate

active

06949378

ABSTRACT:
The invention relates to the identification of gro-1 gene and to demonstrate that the gro-1 gene is involved in the control of a central physiological clock. Also disclosed are four other genes located within the same operon as the gro-1 gene.

REFERENCES:
Verma et al Nature, 1997, vol. 389, pp. 239-242.
Eck et al, Gene-Based Therapy, In: The Pharmacological Basis of Therapeutics, Goodman and Gilman, Ed.s, 1996, pp. 77-101.
Orkin et al “Report and Recommendation of the Panel to Assess the NIH Investment in Research on Gene Therapy”, NIH, 1995).
Houdebine, Journal of Biotechnology, 1994, vol. 34, pp. 269-287.
(Alberts p. 585, Molecular Biology of the Cell, 1989).
Smerdon et al, In: DNA Damage and Repair (monograph), vol. II, pp. 210-212.
Ushijima et al (1997, PNAS, vol. 94, pp. 2284-2289.
Jones et al (PNAS, 1997, vol. 94, pp. 2103-2105.
Hudson (Accession No. G24438, May 31, 1996).
Accession No. BM721352, Mar. 2, 2002.
Bork, Nature Genetics, 1998, vol. 18, pp. 313-318.
Alberts et al, Molecular Boilogy of the Cell, (textbook), 1989, pp. 902.
Bowie et al “Deciphering the Message in protein Sequences:Tolerance to Amino Acid substitutions” Science, vol. 247, pp. 1306-1310, 1990.
Lasar et al, “Transforming Growth Factor Alpha: Mutation of Aspartic Acid 47 and Leuine 48 Results in Different Biological Activities”, Molecular and Cellular Biology, vol. 8, pp. 1247-1252, 1988.
Burgess et al “Possible Dissociation of the Heparin-binding and Mitogenic Activies of Heparin-binding Growth Factor-1 from its Receptor-binding Activities by Site-directed Mutagenesis of a single Lysine Residue”, Journal of Cellular biology, vol. 111, pp, 1990.
P. Bork, “Powers and pitsfalls in sequence analysis”, Genome Research, vol. 10, pp. 398-400, 2000.
Friedburg et al, Ed., DNA Repair and Mutagenesis (Monograph), p. 94, 1995.
PubMed Accession No. D83702, Oct. 1998.
Fu et al, “Translational regulation of human p53 gene expression”, EMBO, vol. 15, pp. 4392-4401, 1996.
Alberts et al, Ed., Molecular Biology of the Cell (textbook), 3rd edition, p. 465, 1994.
Shantz and Pegg, “Translational regulation of ornithine decarboxylase and other enzymes”, International J of Biochemistry and Cell Biology, vol. 31, pp. 107-122, 1999.
McClean and Hill, “Evidence of post-translational regulation of p-glycoprotein”, European J. of Cancer, vol. 29A, pp. 2243-2248, 1993.
Benko et al., “Competition between a sterol biosynthetic enzyme and tRNA modification in addition to changes in the protein synthesis machinery causes altered nonsense suppression” PNAS, Jan. 4, 2000, vol. 97. No. 1, 61-66.
Wilson, R. et al. “2.2 MB of contiguous nucleotide sequence from chromosome III ofC. elegans”, Nature, vol. 368, No. 6466, Mar. 3, 1994, pp. 32-28, XP002029739.
Database EMBL EMINV Entry CEC34E10, Acc. No. U10402, Jun. 30, 1994 Wilson, R. et al.,Caenorhabditis eleganscosmid C34E10′ XP002089545.
Database EMBL—CEZC395 Entry CEZC395, Acc. No. U13642, Nov. 30, 1994 Wilson, R. et al.: “Caenorhabditis eleganscosmid ZC395” XP002089006.
Adams, M. D. et al., “Initial assessment of human gene diversity cDNA sequence” Nature, vol. 377 (6547 Suppl), Sep. 28, 1995, pp. 3-174 XP002042918.
Database EMBL—EMEST14 Entry HSZZ37212, Acc. No. AA332152, Apr. 18, 1997, Adams, M. D. et al.: “EST36068 Embryo, 8 week IHomo sapienscDNA 5′ end similar to similar to tRNA isopentenyltransferase” XP002089546.
Database EMBL—EMEST14 Entry HSZZ61218, Acc. No. AA356092, Apr. 18, 1997 Adams, M. D. et al.: EST64588 Jurkat T-cells VIHomo sapienscDNA 5′ end similar to similar to tRNA isopentenyltransferase. XP002089547.
Stern et al., 1993, “The human GRB2 andDrosophilia Drkgenes can functionally replace theCaenorhabditis eleganscell signaling gene sem-5”Mol. Biol. Cell4:1175-88.
Levitan et al., 1996, “Assessment of normal and mutant human presenilin function inCaenorhabditis elegans” PNAS93:14940-4.
Rugarli, E.I. et al., The Kallman syndrome gene homolog inC. elegansis involved in epidermal morphogenesis and neurite branching, Development 129:pp.1283-1294, 2002.
Gengyo-Ando K., et al., A Murine Neutral-Specific Homolog Corrects Cholinergic Defects inCaenorhabditis elegansunc-18 Mutants, Journal of Neuroscience, 16(21):pp.6695-6702, Nov. 1, 1996.
Antoshechkin, I and Han M., TheC. elegansevl-20 Gene is a Homolog of the Small GTPase ARL2 and Regulates Cytoskeleton Dynamics during Cytokinesis and Morphogenesis, Developmental Cell, 2:pp.579-591, May 2002
Baumeister, R. et al., Human presenilin-1, but not familial Alzheimer's disease (FAD) mutants, facilitateCaenorhabditis elegansNotch signalling independently of proteolytic processing, Genes Funct, 1(2):pp. 149-59, Apr. 1997.
Westmoreland, J.J. et al., Conserved Function ofCaenorhabditis elegansUNC-30 and Mouse Pitx2 in Controlling GABergic Neuron Differentiation, The Journal of Neuroscience, 21(17):pp.6810-6819, Sep. 2001.
Zhang, J. et al., Evolutionary Conservation of MyoD Function and Differential Utilization of E Proteins, Developmental Biology, 208:pp. 465-472, 1999.
Takahashi, M. et al., Mouse coq7/clk-1 Orthologue Rescued Slowed Rhythmic Behavior and Extended Life Span of clk-1 Longevity Mutant inCaenorhabditis elegans, Biochemical and Biophysical Research Communications, 286:pp.534-540, 2001.
Vaux D.L. et al., Prevention of programmed cell death cell death inCaenorhabditis elegansby human bcl-2, Science, 258(5090):pp.1955-1957, Dec. 18, 1992.
Laible, G. et al., Mammalian homologues of the Polycomb-group gene Enhancer of zeste mediate gene silencing inDrosophila heterochromatinand atS. cerevisiae telomeres, The EMBO Journal, 16(11):pp.3219-3232, 1997.
Hudson, J.B. et al., TheDrosophila Medeagene is required downstream of dpp and enclodes a functional homolog of human Smad4, Development 125,pp.1407-1420, 1998.
Wang, J. et al., Mouse Homolog of theDrosophila Pc-GGene esc Exerts a Dominant Negative Effect inDrosophila, Genesis, 26:pp.67-76 , 2000.
Li, X. et al., Isolation and characterization of the putative nuclear modifier gene MTO1 involved in the pathogenesis of deafness-associated mitochondrial 12S rRNA A1555G mutation, Journal of Biological Chemistry Papers in Press, Manuscript—M203267200, Published May 14, 2002.
Lindsey, L.A. et al., Functional Conservation of the Human Homolog of the Yeast Pre-mRNA Splicing Factor Prp17p, The Journal of Biological Chemistry, 273(49):pp.32771-32775, 1998.
Queimado, L. et al., Cloning the human and mouse MMS19 genes and functional complementation of a yeast mms 19 deletion mutant, Nucleic Acids Research, 29(9):pp.1884-1891, 2001.
Ohi, R. et al., Myb-RelatedSchizosaccharomyces pombecdc5p Is Structurally and Functionally Conserved in Eukaryotes, Molecular and Cellular Biology, 18(7):pp.4097-4108, Jul. 1998.
Nikawa, J. et al., Structural and functional conservation of human and yeast HCP1 genes which can suppress the growth defect of theSaccharomyces cerevisiaeire15 mutant, Gene, 171:pp.107-111, 1996.
Dotan, I. et al., Functional Conservation between the Human, Nematode, and Yeast CK2 Cell Cycle Genes, Biochemical and Biophysical Research Communications, 288:pp.603-609, 2001.
Adams, A.E.M., et al., Isoform-Specific Complementation of the Yeast sac6 Null Mutation by Human Fimbrin, Molecular and Cellular Biology,pp. 69-75, Jan. 1995.
Kissil, J.L. et al., Structure-function analysis of an evolutionary conserved protein, DAP3, which mediates TNF-a- and Fas-induced cell death, The EMBO Journal, 18(2):pp.353-362, 1999.
Rothbacher, U. et al., Functional Conservation of the Wnt Signaling Pathway Revealed by Ectopic Expression ofDrosophiladishevelled inXenopus, Developmental Biology, 170:pp.717-721, 1995.
Buzanska, L., et al., Human Medulloblastoma Cell Line DEV Is a Potent Tool to Screen for Factors Influencing Differentiation of Neural Stem Cells, Journal of Neuroscience Research, 65:17-23, 2001.
Fossett, N. and Schulz, R., Functional conservation o

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