C-5 Substituted uracil nucleosides

Drug – bio-affecting and body treating compositions – Conjugate or complex of monoclonal or polyclonal antibody,... – Conjugated via claimed linking group – bond – chelating agent,...

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536 23, A61K 3170, C07H 1700

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active

042475449

ABSTRACT:
Compounds of the formula ##STR1## wherein R.sub.o is --CH.dbd.CH--CH.sub.3 or --CH.dbd.CH--CF.sub.3 and R is .beta.-D-ribofuranosyl, .beta.-D-2-deoxyribofuranosyl or .beta.-D-arabinofuranosyl are useful as antiviral agents.

REFERENCES:
patent: 3282921 (1966-11-01), Verheyden et al.
Montgomery et al., J. Heterocycl. Chem., 2, 313 (1965).
Bergstrom, et al., J. Am. Chem. Soc., 98, 1587 (1976).
Kulikowski et al., J. Med. Chem., 17, 269 (1974).

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