Drug – bio-affecting and body treating compositions – Conjugate or complex of monoclonal or polyclonal antibody,... – Conjugated via claimed linking group – bond – chelating agent,...
Patent
1982-09-13
1984-04-17
Brown, Johnnie R.
Drug, bio-affecting and body treating compositions
Conjugate or complex of monoclonal or polyclonal antibody,...
Conjugated via claimed linking group, bond, chelating agent,...
536 71, A61K 3171, C07H 1708
Patent
active
044434367
ABSTRACT:
C-20-Modified derivatives of the macrolide antibiotics tylosin, desmycosin, macrocin, lactenocin, 2"'-O-demethylmacrocin and 2"-O-demethyllactenocin inhibit pathogenic bacteria, especially gram-positive bacteria, Pasteurella species, and Mycoplasma species and pharmaceutical compositions thereof.
REFERENCES:
patent: 3178341 (1965-04-01), Hamill et al.
patent: 3326759 (1967-06-01), Hamill et al.
patent: 4196280 (1980-04-01), Umezawa et al.
patent: 4268665 (1981-05-01), Sakakibara et al.
patent: 4279896 (1981-07-01), Ganguly et al.
patent: 4299953 (1981-11-01), Hamill et al.
patent: 4321361 (1982-03-01), Baltz et al.
patent: 4321362 (1982-03-01), Baltz et al.
patent: 4345069 (1982-08-01), Sakakibara et al.
patent: 4349665 (1982-09-01), Lee et al.
patent: 4357325 (1982-11-01), Ose et al.
Matsubara et al., "Chemical Transformation of Tylosin, a 16-Membered Macrolide and its Structure-Activity Relationship", Chem. Pharm. Bull. 30 (1), 97-110 (1982).
S. Omura et al., "Novel Dimeric Derivatives of Leucomycins and Tylosin, Sixteen-Membered Macrolides", J. Med. Chem. 25, 271-275 (1982).
Derwent Abstract No. 71396Y of Japanese Unexamined Patent 2100-485 (Takeda), Aug. 23, 1977.
A. Tanaka et al., "Syntheses of 4'-Deoxy-Demycarosyl Tylosin and Its Analogues", J. Antibiotics 34 (10), 1381-1384 (1981).
S. Satoi et al., "Mycinamicins, New Macrolide Antibiotics. I: Taxonomy, Production, Isolation, Characterization and Properties", J. Antibiotics 33 (4), 364-377 (1980).
Kirst Herbert A.
Toth John E.
Brown Johnnie R.
Eli Lilly and Company
Harrison Nancy J.
Peselev Elli
Whale Arthur R.
LandOfFree
C-20-Modified macrolide derivatives of the macrolide antibiotics does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with C-20-Modified macrolide derivatives of the macrolide antibiotics, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and C-20-Modified macrolide derivatives of the macrolide antibiotics will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-95173