C-20-dihydro-deoxy-(cyclic amino)-derivatives of macrolide antib

Details C-20-dihydro-deoxy-(cyclic amino)-derivatives of macrolide antib C-20-dihydro-deoxy-(cyclic amino)-derivatives of macrolide antib

1987-05-28

1989-04-11

Brown, Johnnie R.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

536 71, A61K 3171, C07H 1708

Patent

active

048206954

ABSTRACT:
C-20-Dihydro-deoxy-(cyclic amino)-derivatives of the macrolide antibiotics tylosin, desmycosin, macrocin, lactenocin, 2"'-O-demethylmacrocin and 2"-O-demethyllactenocin, which inhibit pathogenic bacteria, especially gram-positive bacteria, Pasteurella species, and Mycoplasma species, and pharmaceutical compositions thereof, are provided.

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H. Matsubara et al., "Chemical Modification of Tylosin: Synthesis of Amino Derivatives at C-20 Position of Tylosin and Demycarosyltylosin", J. Antibiotics 36, 1713-1721, (1983).
Derwent Abstract No. 84-110819/18 of Japanese Unexamined Patent J5 9051-299A (Zh Biseibutsu Kagaku Ken), Mar. 24, 1984.

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