Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Patent
1984-05-25
1986-12-16
Brown, Johnnie R.
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
C07H 1708
Patent
active
046297863
ABSTRACT:
C-20-Modified derivatives of macrolide antibiotics which include demycinosyltylosin (DMT), 20-dihydro-23-demycinosyltylosin (dihydro-DMT), 23-de(mycinosyloxy)tylosin (DMOT), 20-dihydro-23-de(mycinosyloxy)tylosin (dihydro-DMOT), 5-O-mycaminosyltylonolide (OMT), 20-dihydro-5-O-mycaminosyltylonolide (dihydro-OMT), 23-deoxy-5-O-mycaminosyltylonolide (DOMT), and 20-dihydro-23-deoxy-5-O-mycaminosyltylonolide (dihydro-DOMT) inhibit pathogenic bacteria, especially gram-positive bacteria, and Mycoplasma species; and pharmaceutical compositions thereof.
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Debono Manuel
Kirst Herbert A.
Brown Johnnie R.
Eli Lilly and Company
Harrison Nancy J.
Peselev Elli
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