Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Ester doai
Reexamination Certificate
2009-09-14
2011-12-27
Padmanabhan, Sreeni (Department: 1627)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Ester doai
C514S579000
Reexamination Certificate
active
08084497
ABSTRACT:
Pharmaceutical formulations of [2-(3-methoxyphenyl)-cyclohexylmethyl]-dimethylamine and the metabolites thereof suitable for treating fibromyalgia or chronic pain due to fibromyalgia, and related methods of treating fibromyalgia or chronic pain due to fibromyalgia are described.
REFERENCES:
patent: 5733936 (1998-03-01), Buschmann et al.
patent: 195 25 137 (1997-01-01), None
patent: 102 54 785 (2004-06-01), None
patent: WO 02/43712 (2002-06-01), None
patent: WO 02/067651 (2002-09-01), None
patent: WO 2004/009067 (2004-01-01), None
patent: WO 2004/047823 (2004-06-01), None
patent: WO 2006/094961 (2006-09-01), None
patent: WO 2007/031326 (2007-03-01), None
Lavin et al. “Use of the Leeds Assessment of Neuropathic Symptoms and Signs Questionnaire in Patients with Fibromyalgia” Seminars in Arthritis and Rheumatism, vol. 32, No. 6 Jun. 2003: pp. 407-411.
Rao et al. “Pharmacological therapies in fibromyalgia” Best Practice & Research Clinical Rheumatology vol. 17, No. 4, pp. 611-627, 2003.
Corresponding European Search Report dated Mar. 6, 2009 with English translation (Six (6) pages).
Flick et al., “Untersuchungen Zur Chemischen Struktur und Analgetischen Wirkung Von Phenylsubstituierten Aminomethylcyclohexanolen” (Studies on Chemical Structure and Analgetic Activity of Phenyl Substituted Aminomethycyclohexanoles), Arzneimittel Forschung. Drug Research, Editio Cantor. Aulendorf, DE, BD. 28, NR. 1A, 1978, pp. 107-113, XP000608150.
Leventhal: “Management of Fibromyalgia”, Annals of Internal Medicine Dec. 7, 1999, vol. 131, Nr. 11, 1999, pp. 850-858, XP002517722.
Bamigrade et al., “Actions of Tramadol, its Enantiomers and Principal Metabolite, O-desmethyltramadol, on Serotonin (5-HT) Efflux and Uptake in the Rat Dorsal Raphe Nucleus”, British Journal of Anasthesia 1997; 79: pp. 352-356.
Halfpenny et al., “Effects of Tramadol Stereolsomers on Norepinephrine Efflux and Uptake in the Rat Locus Coeruleus Measured by Real Time Voltammetry”, British Journal of Angesthesis, 1999, pp. 908-915.
Rojas-Corrales et al., “Tramadolinduces Antidepressant-Type Effects in Mice”, Elsevier Science Life Sciences, vol. 63, No. 12, pp. 175-180, 1998, Elsevier Science, Inc.
Bloms-Funke Petra
Englberger Werner
Hennies Hagen-Heinrich
Claytor Renee
Crowell & Moring LLP
Gruenenthal GmbH
Padmanabhan Sreeni
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