Organic compounds -- part of the class 532-570 series – Organic compounds – Carboxylic acid esters
Reexamination Certificate
2004-07-14
2010-10-26
Zucker, Paul A (Department: 1621)
Organic compounds -- part of the class 532-570 series
Organic compounds
Carboxylic acid esters
C562S470000
Reexamination Certificate
active
07820847
ABSTRACT:
The present invention relates to butenoic acid derivatives of the formula I:in which R, R1, R2and R3are as defined in the description,and also to processes for the preparation thereof, to pharmaceutical compositions comprising them and to their use for the treatment of dyslipidaemia, atherosclerosis and diabetes.
REFERENCES:
patent: 7465752 (2008-12-01), Zeiller et al.
patent: 52 070021 (1977-06-01), None
patent: 2001 261612 (2001-09-01), None
Doyle et al, Tetrahedron Letters, 2002, 43, pp. 5929-5931.
He et al, Journal of the American Chemical Society, Enantioselective Synthesis of a Novel Trans Double Bond Ceramide Analogue via Catalytic Asymmetric Dihydroxylation of an Enyne. The Role of the Trans Double Bond of Ceramide in the Fusion of Semiliki Forest Virus with Target Membranes, 1999, 121(16), pp. 3897-3903.
Davies et al, Tetrahedron Letters, Regiochemistry of Molybdenum-catalyzed O-H Insertions of Vinylcarbenoids, 2000, 41, pp. 4851-4854.
Bergmann et al, Journal of Organic Chemistry, Note on Preparation of Cyclohexen-1-aldehyde, 1958, 23, pp. 1553-1554.
Landais et al, Synlett, Electronic Versus Steric Effects in 5-endo-trig-like Electrophilic Cyclization, 1995, (11) pp. 1191-1193.
Database CA ′Online! Chemical Abstracts Service, Columbus, Ohio, US; Katsuda, Yoshio et al: “Insecticides” XP002274456 retrieved from STN Database accession No. 88:46409 abstract.
Database CA ′Online! Chemical Abstracts Service, Columbus, Ohio, US: Supniewski, J. et al: “p-(Diethylamino) EthoxyiPhenyl-P-Tolyl-P-Fluorophenylethanol” XP002274457, Retrieved from STN Database accession No. 59:41367 abstract.
Lin Li He: “Enantioselective Synthesis of a Novel Trans Double Bond Ceramide Analogue Via Catalytic Asymetric Dihydroxylation of an Enyne” J.A.C.S., No. 121, 1999, pp. 3897-3903, XP002274453.
Mariko Aso: “Successive Michael Reaction-Sigmatropic Rearrangement of Polyquinones With Silyl Ketene Acetals” J.O.C., vol. 54, No. 23, 1989, pp. 5597-5603, XP002274454.
Database CA ′Online: Chemical Abstracts Service, Columbus, Ohio, US; Savard Jacques: “Reactions of Ketene Acetals-14. The Use of Simple Mixed Vinylketene Acetals in the Annulation of Quinones” XP002274458 Database accession No. 1985:131682 abstract & Tetrahedron, vol. 40, No. 18, 1984, pp. 3455-3464.
Doyle M P et al: “Chiral Catalyst Enhancement of Diastereocontrol for O@?H Insertion Reactions of Styryl-and Phenyldiazoacetate Esters of Pantolactone” Tetrahedron Letters, Elsevier Science Publishers, Amsterdam, NL, vol. 43, No. 34, Aug. 19, 2002, pp. 5929-5931, XP004373202; ISSN: 0040-4039.
Davies H M L et al: “Regiochemistry of Molybdenum-Catalyzed O-H Insertions of Vinylcarbenoids” Tetrahedron Letters, Elsevier Science Publishers, Amsterdam, NL, vol. 41, No. 25, Jun. 2000, pp. 4851-4854, XP004205669; ISSN: 0040-4039.
Y. Landais: A Stereospecific Access to Allylic Systems Using Rhodium (II)-Vinyl Carbenoid Insertion Into Si-H, O-H and N-H Bonds: J. Org. Chem., No. 62, 1997, pp. 1630-1641, XP002274455.
Database Crossfire Beilstein ′Online! Beilstein Institut Zur Förderung Der Chemischen Wissenschaften, Frankfurt Am Main, DE; Jarosz Slawomir: XP002274459; Database accession No. 3898752 abstract & Tetrahedron, vol. 38, No. 10, 1982, pp. 1447-1452.
Database Crossfire Beilstein ′Online! Beilstein Institut Zur Förderung Der Chemischen Wissenschaften, Frankfurt Am Main, DE; Guss: XP002274460; Database accession No. 439330 abstract & J.A.C.S., No. 71, 1949.
Patent Abstracts of Japan vol. 2000, No. 26, Jul. 1, 2002.
Berard Isabelle
Bonhomme Yves
Contard Francis
Dumas Herve
Ferrand Gerard
Merck Patent GmbH
Millen White Zelano & Branigan P.C.
Zucker Paul A
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