Butadiene derivatives and process for using the same

Details Butadiene derivatives and process for using the same Butadiene derivatives and process for using the same

1995-05-08

1997-06-17

Haley, Jacqueline

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Ester doai

5142378, 514354, 514355, 514357, 544162, 546316, 546323, 546335, 560 39, 560 41, C07D40106, A61K 3144

Patent

active

056397895

ABSTRACT:
Novel butadiene derivatives of the formula [I]: ##STR1## wherein Ring A is tri-lower alkoxyphenyl, R.sup.1 and R.sup.2 combine each other to form a group of the formula: ##STR2## or one of R.sup.1 and R.sup.2 is lower alkoxy, and the other is group of the formula: -NHR.sup.3, in which R.sup.3 is hydrogen, substituted or unsubstituted lower alkyl, substituted or unsubstituted lower alkoxy, substituted or unsubstituted amino, hydroxy or pyridylcarbonyl, or salts thereof, these compounds have excellent antithrombotic activity and are useful as antithrombotic drug, or synthetic intermediate for preparing other antithrombotic drug.

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