Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Chemical modification or the reaction product thereof – e.g.,...
Reexamination Certificate
2006-10-06
2008-09-09
Le, Long V. (Department: 1641)
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Chemical modification or the reaction product thereof, e.g.,...
C530S402000, C530S405000, C530S408000, C530S807000, C436S056000, C436S544000, C436S528000, C435S007100, C435S007920, C435S007930
Reexamination Certificate
active
07423131
ABSTRACT:
Novel conjugates of busulfan and novel busulfan immunogens derived from α-substituted derivatives of busulfan and antibodies generated by these busulfan linked immunogens are useful in immunoassays for the quantification and monitoring of busulfan in biological fluids.
REFERENCES:
patent: 5430057 (1995-07-01), Anderson et al.
Murdter et al. Sensitive and rapid quantification of Busulfan in small plasme volumes by liquid chromatography electrospray mass spectrometry. Clinical Chemistry 2001, vol. 47, pp. 1437-1442, whole document.
Lai et al. Routine analysis of plasma busulfan by gas chromatography-mass freagmentography. Clinical Chemistry 1998, vol. 44, pp. 2506-2510, whole document.
Reis et al. Development of a rapid and specific assay for detection of busulfan in human plasma by high performance liquid chromatorgraphy/electrospray ionization tandem mass spectometry. Rapid Communication in Mass Spectrometry. 2004, vol. 19, pp. 1666-1674.
The International Preliminary Report on Patentability by the International Bureau of WIPO, issued on Mar. 29, 2007, in the PCT application No. PCT/US2005/032789.
Courtney Jodi Blake
He Shu
Salamone Salvatore J.
Haq Shafiqul
Le Long V.
Saladax Biomedical Inc.
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