Chemistry: analytical and immunological testing – Including sample preparation – Liberation or purification of sample or separation of...
Reexamination Certificate
2007-05-22
2007-05-22
Wallenhorst, Maureen M. (Department: 1743)
Chemistry: analytical and immunological testing
Including sample preparation
Liberation or purification of sample or separation of...
C436S045000, C436S063000, C422S051000, C422S051000, C422S067000, C422S072000, C422S073000, C422S105000, C422S105000, C435S002000, C210S782000
Reexamination Certificate
active
10263974
ABSTRACT:
A tube and float system for use in separation and axial expansion of the buffy coat includes a transparent or semi-transparent, flexible sample tube and a rigid separator float having a specific gravity intermediate that of red blood cells and plasma. The float includes a main body portion of reduced diameter to provide a clearance gap between the inner wall of the sample tube and the float. One or more protrusions on the main body portion serve to support the flexible tube. During centrifugation, the centrifugal force causes the diameter of the flexible tube to expand and permit density-based axial movement of the float in the tube. The float further includes a pressure relief system to alleviate pressure build up in the trapped red blood cell blood fraction below the float, thereby preventing red blood cells from being forced into the annular gap containing the buffy coat layers.
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Contini Vince
Grimes Steve
Haubert Thomas
Jones Randy
Wardlaw Stephan C.
Battelle (Memorial Institute)
Fay Sharpe LLP
Wallenhorst Maureen M.
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