Drug – bio-affecting and body treating compositions – Topical body preparation containing solid synthetic organic... – Anti-inflammatory or anti-irritant
Patent
1993-10-06
1994-11-08
Page, Thurman K.
Drug, bio-affecting and body treating compositions
Topical body preparation containing solid synthetic organic...
Anti-inflammatory or anti-irritant
424 7806, 424401, 424402, 514865, 514969, A61K 3174, A61K 900
Patent
active
053624882
ABSTRACT:
A buffered skin cream containing a linear polydimethylsiloxane polymer, a non-ionic emulsifier, aloe vera, mineral oil, sodium citrate, citric acid, a blend of propylene glycol, diazolidinyl urea, methyl paraben and propyl paraben, and water. The buffering capacity of the cream is provided through the incorporation of citric acid and sodium citrate in the composition. The buffering system results in the cream having a preferred pH in the range of about 4.5 to 6.0, and most preferably a pH of about 5.2 which neutralizes acidic and basic by-products of urine and fecal matter. The cream has a preferred viscosity in the range of 100,000-2,000,000 centipoise and a most preferred viscosity of about 250,000 to 1,000,000 centipoise. The cream is easily washed off with soap and water and is useful in the protection and treatment of diaper rash.
REFERENCES:
patent: 4536399 (1985-08-01), Flynn
patent: 4556560 (1985-12-01), Buckingham
patent: 4808388 (1989-02-01), Beutler
patent: 4904524 (1990-02-01), Yoh
patent: 4996238 (1991-02-01), Matrevers
The Practitioner, vol. 210: 824-828 (1973); Reports from Gen'l Practitioner Research Group.
Hartung Donald E.
Ruland Rosalyn
Sibley Murray J.
Abbott Laboratories
Drayer Lonnie R.
Gardner Sally
Nickey Donald O.
Page Thurman K.
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