Drug – bio-affecting and body treating compositions – Whole live micro-organism – cell – or virus containing – Animal or plant cell
Reexamination Certificate
2006-11-14
2006-11-14
Saucier, Sandra E. (Department: 1651)
Drug, bio-affecting and body treating compositions
Whole live micro-organism, cell, or virus containing
Animal or plant cell
C424S427000, C623S004100
Reexamination Certificate
active
07135172
ABSTRACT:
A method for repairing a retinal system of an eye, using bucky paper on which a plurality of retina pigment epithelial cells and/or iris pigment epithelial cells and/or stem cells is deposited, either randomly or in a selected cell pattern. The cell-covered bucky paper is positioned in a sub-retinal space to transfer cells to this space and thereby restore the retina to its normal functioning, where retinal damage or degeneration, such as macular degeneration, has occurred.
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R.D. Lund et al. (2001). “Subretinal transplantation of genetically modified human cell lines attenuates loss of visual function in dystrophic rats,” Proceedings of the National Academy of Sciences, U.S.A. vol. 98, pp. 9942-9947.
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Leng et al., “Carbon nanotube bucky paper as an artificial support membrane and Bruch's membrane patch in subretinal RPE and IPE transplantation”, ARVO Annual Meeting Abstract Search and Program Planner, 2003, abstract 481, (2003).
Woch, Gustaw, et al., Retinal Transplants Restore Visually Evoked Responses in Rats with Photoreceptor Degeneration, IOVS, Jun. 2001, 1669-1676, vol. 42, No. 7, Association for Research in Vision and Opthalmology.
Fishman Harvey
Huie Philip
Leng Theodore
Loftus David J.
Padilla Robert M.
Saucier Sandra E.
Schipper John F.
The United States of America as represented by the Administrator
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