Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Implant or insert
Patent
1996-04-12
1999-09-21
Azpuru, Carlos
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Implant or insert
424 45, A61L 904
Patent
active
059550988
ABSTRACT:
A buccal aerosol spray or capsule using a non-polar solvent has now been developed which provides biologically active compounds for rapid absorption through the oral mucosa, resulting in fast onset of effect. The buccal aerosol spray of the invention comprises formulation I: propellant 50-95%, non-polar solvent 5-50%, active compound 0.001-15%, flavoring agent 00.05-5%. The soft bite gelatin capsule of the invention comprises formulation II: non-polar solvent 55-99.8%, emulsifier 0-20%, active compound 0.001-25%, and flavoring agent 0.05-5.0%.
REFERENCES:
patent: 4935243 (1990-06-01), Borkan et al.
patent: 5428006 (1995-06-01), Bechgaard et al.
Rote Liste 1995, "Arzneimittelverzeichnis des BPI und VFA".
Azpuru Carlos
Behr Esq. Omri M.
Flemington Pharmaceutical Corp.
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