Buccal non polar spray or capsule

Details Buccal non polar spray or capsule Buccal non polar spray or capsule

1996-04-12

1999-09-21

Azpuru, Carlos

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Implant or insert

424 45, A61L 904

Patent

active

059550988

ABSTRACT:
A buccal aerosol spray or capsule using a non-polar solvent has now been developed which provides biologically active compounds for rapid absorption through the oral mucosa, resulting in fast onset of effect. The buccal aerosol spray of the invention comprises formulation I: propellant 50-95%, non-polar solvent 5-50%, active compound 0.001-15%, flavoring agent 00.05-5%. The soft bite gelatin capsule of the invention comprises formulation II: non-polar solvent 55-99.8%, emulsifier 0-20%, active compound 0.001-25%, and flavoring agent 0.05-5.0%.

REFERENCES:
patent: 4935243 (1990-06-01), Borkan et al.
patent: 5428006 (1995-06-01), Bechgaard et al.
Rote Liste 1995, "Arzneimittelverzeichnis des BPI und VFA".

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