Buccal, non-polar spray for nitroglycerin

Details Buccal, non-polar spray for nitroglycerin Buccal, non-polar spray for nitroglycerin

1996-04-12

1999-02-09

Azpuru, Carlos A.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Implant or insert

424434, 424 45, A61F 1302, A61L 904

Patent

active

058690824

ABSTRACT:
A buccal aerosol spray using a non-polar solvent has now been developed which provides nitroglycerin for rapid absorption through the oral mucosa, resulting in fast onset of effect. The buccal aerosol spray of the invention comprises: propellant 50-95%, non-polar solvent 5-50%, nitroglycerin 0.001-15%, flavoring agent 0.05-5%.

REFERENCES:
patent: 5428006 (1995-06-01), Bechgaard et al.

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