Buccal delivery system for therapeutic agents

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Implant or insert

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424484, 424486, A61F 1300

Patent

active

058275258

ABSTRACT:
A unidirectional buccal delivery system for the delivery of therapeutic agents over an extended period of time. The delivery system includes a matrix for releasing the drug into the oral cavity at a sustained rate and a means for securing the matrix to the palate or other adequate regions in the oral cavity.

REFERENCES:
patent: 4538603 (1985-09-01), Pawelchak et al.
patent: 4551490 (1985-11-01), Doyle et al.
patent: 5455043 (1995-10-01), Fischel-Ghodisian
patent: 5607691 (1997-03-01), Hale
John D. Smart, "Drug delivery using buccal-adhesive systems", Advanced Drug Delivery Reviews, 11 (1993) pp. 253-270.
M. R. Rassing, "Chewing gum as a drug delivery system", Advanced Drug Delivery Reviews, 13 (1994) pp. 89-121.

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