Bubble-free and pressure-generating electrodes for...

Details Bubble-free and pressure-generating electrodes for... Bubble-free and pressure-generating electrodes for...

2008-04-15

2008-04-15

Noguerola, Alex (Department: 1795)

Chemistry: electrical and wave energy

Apparatus

Electrophoretic or electro-osmotic apparatus

C204S601000, C422S050000, C422S070000

Reexamination Certificate

active

10984239

ABSTRACT:
Bubble-free electrodes, electrochemical cells including bubble-free electrodes, analytical devices, and methods for preparing and using them are provided. The analytical devices each include at least one bubble-free electrode. Analytical devices that include an electrochemical cell and a sample containment device are also provided, wherein the electrochemical cell includes an anodic reservoir, a cathodic reservoir, an electrical connection between the anodic reservoir and the cathodic reservoir, and a first bubble-free electrode disposed within one of the anodic reservoir and the cathodic reservoir. A second electrode is disposed within the other reservoir and a power source is provided having a positive terminal that is normally in electrical contact with the first electrode, and a negative terminal that is normally in electrical contact with the second electrode. The analytical device further includes a power source polarity-inverting device for switching the contacts between the terminals of the power source and the first and second electrodes. The sample containment device includes a sample containment chamber having an opening for introducing a sample into the chamber and being positioned with respect to the electrochemical cell such that an electrical field generated by the electrochemical cell can influence a property of a component of a sample disposed in the sample containment chamber. Pressure-generating cells are also provided.

REFERENCES:
patent: 3969218 (1976-07-01), Scott
patent: 4001100 (1977-01-01), Haydock
patent: 4154669 (1979-05-01), Goetz
patent: 4351709 (1982-09-01), Goetz
patent: 5035790 (1991-07-01), Morimoto et al.
patent: 5126022 (1992-06-01), Soane et al.
patent: 5240576 (1993-08-01), Lauer et al.
patent: 5384024 (1995-01-01), Moring et al.
patent: 5540831 (1996-07-01), Klein
patent: 5605662 (1997-02-01), Heller et al.
patent: 5624539 (1997-04-01), Ewing et al.
patent: 5632957 (1997-05-01), Heller et al.
patent: 5833826 (1998-11-01), Nordman
patent: 5849486 (1998-12-01), Heller et al.
patent: 5858187 (1999-01-01), Ramsey et al.
patent: 5965452 (1999-10-01), Kovacs
patent: 6001229 (1999-12-01), Ramsey
patent: 6045676 (2000-04-01), Mathies et al.
patent: 6068818 (2000-05-01), Ackley et al.
patent: 6071394 (2000-06-01), Cheng et al.
patent: 6077625 (2000-06-01), Yano et al.
patent: 6099803 (2000-08-01), Ackley et al.
patent: 6102897 (2000-08-01), Lang
patent: 6103199 (2000-08-01), Bjornson et al.
patent: 6129828 (2000-10-01), Sheldon, III et al.
patent: 6159353 (2000-12-01), West et al.
patent: 6174675 (2001-01-01), Chow et al.
patent: 6236945 (2001-05-01), Simpson et al.
patent: 6245508 (2001-06-01), Heller et al.
patent: 6267864 (2001-07-01), Yadav et al.
patent: 6379516 (2002-04-01), Cabilly et al.
patent: 6416642 (2002-07-01), Alajoki et al.
patent: 6458259 (2002-10-01), Parce et al.
patent: 6471841 (2002-10-01), Nikiforov et al.
patent: 6476539 (2002-11-01), Takeuchi et al.
patent: 6569306 (2003-05-01), Read et al.
patent: 2002/0054835 (2002-05-01), Robotti et al.
patent: 2002/0166592 (2002-11-01), Liu et al.
patent: 63302532 (1988-12-01), None
patent: WO 94/29707 (1994-12-01), None
patent: WO 98/00893 (1998-01-01), None
patent: WO 98/09161 (1998-03-01), None
patent: WO 98/48084 (1998-10-01), None
patent: WO 98/49549 (1998-11-01), None
patent: WO 99/14368 (1999-03-01), None
patent: WO 99/29711 (1999-06-01), None
patent: WO 99/49319 (1999-09-01), None
patent: WO 99/50480 (1999-10-01), None
patent: WO 00/37163 (2000-06-01), None
patent: WO 00/42424 (2000-07-01), None
patent: WO 00/73780 (2000-12-01), None
patent: WO 00/74850 (2000-12-01), None
Alien Technology document or printout for 185 and 70 Micorn NanoBlock circuits on top of a dime, and flexible PET substrate, one page (not dated).
International Search Report from PCT/US02/26657 dated Dec. 9, 2002.
U.S. Appl. No. 09/938,894, to Bryning et al., entitled “Manipulation of Analytes Using Electric Fields” filed Aug. 24, 2001.
Alien Technology document or printout for 185 and 70 Micron NanoBlock circuits on top of a dime, and flexible PET substrate, one page (not dated).
Becker et al., Polymer Microfabrication Methods for Microfluidic Analytical Applications,Electrophoresis, vol. 21, pp. 12-26 (2000).
Bruin, Recent Developments in Electrokinetically Driven Analysis on Microfabricated Devices,Electrophoresis, vol. 21, pp. 3931-3951 (2000).
Campaña et al., Miniaturization of Capillary Electrophoresis Systems Using Micromachining Techniques,Journal of Microcolumn Separation, vol. 10, No. 4, pp. 339-355 (1998).
Carrilho, DNA Sequencing by Capillary Array Electrophoresis and Microfabricated Array Systems,Electrophoresis, vol. 21, pp. 55-65 (2000).
Dolník et al., Capillary Electrophoresis on Microchip,Electrophoresis, vol. 21, pp. 41-54 (2000).
Granger et al., Standard Electrochemical Behavior of High-Quality, Boron-Doped Polycrystalline Diamond Thin-Film Electrodes,Analytical Chemistry, vol. 72, No. 16, pp. 3793-3804 (Aug. 15, 2000).
Huang et al., Electric Manipulation of Bioparticles and Macromolecules on Microfabricated Electrodes,Analytical Chemistry, vol. 73, No. 7, pp. 1549-1559 (Apr. 1, 2001).
Krishnamoorthy et al., Analysis of Sample Injection and Band-Broadening in Capillary Electrophoresis Microchips,Modeling and Stimulation of Microsystems, Applied Computational Research Society, vol. 3 (2000).
Liu et al., Optimization of High-Speed DNA Sequencing on Microfabricated Capillary Electrophoresis Channels,Analytical Chemistry, vol. 71, No. 3, pp. 566-573 (Feb. 1, 1999).
McDonald et al., Fabrication of Microfluidic Systems in Poly(dimethylsiloxane),Electrophoresis, vol. 21, pp. 27-40 (2000).
Morgan et al., Separation of Submicron Bioparticles by Dielectrophoresis,Biophysical Journal, vol. 77, pp. 516-525 (Jul. 1999).
Morishima et al., Transportation of DNA Molecule Utilizing the Conformational Transition in the Higher Order Structure of DNA,CCAB 97published on the internet on Feb. 13, 1998.
Nanogen document or printout for NanoChip Molecular Biology Workstation, one page, showing workstation with enlargement of 99-site test array (not dated).
Rocklin et al., A Microfabricated Fluidic Device for Performing Two-Dimensional Liquid-Phase Separations,Analytical Chemistry, vol. 72, No. 21, pp. 5244-5249 (Nov. 1, 2000).
Simpson et al., A Transmission Imaging Sepctrograph and Microfabricated Channel System for DNA Analysis,Electrophoresis, vol. 21, pp. 135-149 (2000).
Washizu et al., Molecular Dielectrophoresis of Biopolymers,IEEE Transactions on Industry Applications, vol. 30, No. 4, pp. 835-843 (Jul./Aug. 1994).
Waters et al., Microchip Device for Cell Lysis, Multiplex PCR Amplification, and Electrophoretic Sizing,Analytical Chemistry, vol. 70, pp. 158-162 (1998).
Woolley et al., Capillary Electrophoresis Chips with Integrated Electrochemical Detection,Analytical Chemistry, vol. 70, pp. 684-688 (1998).
Woolley et al., Functional Integration of PCR Amplification and Capillary Electrophoresis in a Microfabricated DNA Analysis Device,Analytical Chemistry, vol. 68, pp. 4081-4086 (1996).
Woolley et al., Ultra-High Speed DNA Fragment Separations Using Microfabricated Capillary Array Electrophoresis Chips,Proceedings of the National Academy of Sciences, USA vol. 91, pp. 11348-11352 (1994).
Xu et al., Boron-Doped Diamond Thin-Film Electrodes,Analytical Chemistry, vol. 69, pp. 591A-597A (Oct. 1, 1997).
Zak et al., Diamond Optically Transparent Electrodes: Demonstration of Concept with Ferri/Ferrocyanide and Methyl Viologen,Analytical Chemistry, vol. 73, No. 5, pp. 908-914 (Mar. 1, 2001).
Communication from EPO for European Patent Application No. EP02757289.0, dated Aug. 31, 2007.
Supplementary European Search Report dated Aug. 23, 2007, with related Annex, from European Patent Application No. EP02757289.0.

Affiliated with

Also associated with

Rating

Bubble-free and pressure-generating electrodes for... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Bubble-free and pressure-generating electrodes for..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Bubble-free and pressure-generating electrodes for... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-3934616