BU-3292T antibiotics

Details BU-3292T antibiotics BU-3292T antibiotics

1988-09-14

1992-05-19

Ivy, C. Warren

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514 10, 530317, A61K 3702, C07K 700

Patent

active

051149206

ABSTRACT:
New antibiotics designated BU-3292T A and B are provided which exhibit antimicrobial activity and also inhibit the growth of tumors in experimental animal systems. BU-3292T A is produced by fermentation of Elytrosporangium sp. nov. (ATCC 53784) while the BU-3292T B compound is obtained by oxidation of BU-3292T A.

REFERENCES:
Meienhofer "Synthesis of actinomycin . . . " J. Am. Chem. Soc. 92(12) 3771-3777 (1970).
Meienhofer et al "Structure-Activity . . . " in Structure activity Relationship . . . ed. D. Perlman, 1977, pp. 488-494.

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