Bt toxin receptors from lepidopteran insects

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues

Reexamination Certificate

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C530S402000

Reexamination Certificate

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07572889

ABSTRACT:
The invention relates to Bt toxin resistance management. The invention particularly relates to the isolation and characterization of nucleic acid and polypeptides for a novel Bt toxin receptor. The nucleic acid and polypeptides are useful in identifying and designing novel Bt toxin receptor ligands including novel insecticidal toxins.

REFERENCES:
patent: 5693491 (1997-12-01), Bulla et al.
patent: 5804393 (1998-09-01), Geiser et al.
patent: 6007981 (1999-12-01), Bulla
patent: 6423502 (2002-07-01), Bulla et al.
patent: 6660497 (2003-12-01), Bulla et al.
patent: WO 96/12964 (1996-05-01), None
patent: WO 98/59048 (1998-12-01), None
patent: WO 01/34807 (2001-05-01), None
Dorsch, J., “Isolation and Characterization of the Insecticidal Toxin Binding Site From the Receptor BT-R1ofManduca Sexta,” A Dissertation submitted to the Department of Molecular Biology and the Graduate School of the University of Wyoming, 1998.
Estruch, J. et al., “Transgenic Plants: An Emerging Approach to Pest Control,”Nature Biotechnology, 1997, vol. 15, pp. 137-141.
Francis, B., et al., “Further Characterization of BT-R1, The Cadherin-Like Receptor for Cry 1AB Toxin in Tobacco Hornworm (Manduca sexta) Midguts, Insect,”Biochem. Mol. Biol., 1997, vol. 27(6), pp. 541-550.
Franklin, S., et al., “Southern Analysis of BT-R1, TheManduca SextaGene Encoding The Receptor for the CrylAB Toxin ofBacillus Thuringiensis,”Mol. Gen. Genet, 1997, vol. 256, pp. 517-524.
Gahan, L.J., et al., “Identification of a Gene Associated with Bt Resistance in Heliothis Virescens,”Science(2001) pp. 857-860, vol. 293.
Garczynski, S., et al., “Identification of Putative Insect Brush Border Membrane-Binding Molecules Specific toBacillus Thuringiensisδ-Endotoxin by Protein Blot Analysis, Applied Environmental Microbiology,” 1991, vol. 57(10), pp. 2816-2820.
Gill, S, et al., “Identification, Isolation, and Cloning of aBacillus ThuringiensisCrylAc Toxin-Binding Protein from the Midgut of the Lepidopteran Insect Heliothis Virescens,”The Journal of Biological Chemistry, 1995, vol. 270(45), pp. 27277-27282.
Hofte, et al., “Insecticidal Crystal Proteins ofBacillus Thuringiensis,”Microbiological Reviews, 1989, vol. 53(2), pp. 242-255.
Hua, G., et al., “Binding Analyses ofBacillus ThuringiensisCry δ-Endotoxins Using Brush Border Membrane Vesicles ofOstrinia Nubilalis,”Applied and Environmental Microbiology, 2001, vol. 67(2), pp. 872-879.
Ihara, H., et al., “Purification and Partial Amino Acid Sequences of the Binding Protein from Bombyx Mori for CrylAa δ-endotoxin ofBacillus Thuringiensis,”Elsevier Science Inc., 1998, pp. 197-204.
Keeton, T., et al., “Effects of Midgut-Protein-Preparative and Ligand Binding Procedures on the Toxin Binding Characteristics of BT-R1, A Common High-Affinity Receptor in Manduca Sexta for Cryl ABacillus ThuringiensisToxins,”Applied and Environmental Microbiology, 1998, vol. 64(6), pp. 2158-2165.
Keeton, T., et al., “Ligand Specificity and Affinity of BT-R1, TheBacillus ThuringiensisCryl A Toxin Receptor FromManduca Sexta, Expressed in Mammalian and Insect Cell Cultures,”Applied and Environmental Microbiology, 1997, vol. 63(9), pp. 3419-3425.
Knight, P., et al., “The Receptor forBacillus ThuringiensisCrylA(c) Delta-Endotoxin in the Brush Border Membrane of the LepidopteranManduca Sextais Aminopeptidase N,”Molecular Microbiology, 1994, vol. 11(3), pp. 429-436.
Lee, M., et al., “Aminopeptidase N Purified from Gypsy Moth Brush Border Membrane Vesicles Is a Specific Receptor forBacillus ThuringiensisCrylAc Toxin,”Applied and Environmental Microbiology, 1996, vol. 62(8), pp. 2845-2849.
McGaughey, W., et al., “RT Resistance Management A Plan for Reconciling the Needs of the Many Stakeholders in Bt-Based Products,”Nature Biotechnology, 1998, vol. 16, pp. 144-146.
Matty, W.S.A., “Identification, Purification and Cloning of a High-Affinity Invertebrate Protocadherin Receptor BT-R2From the Pink Bollworm (Pectinophora gossypiella) forBacillus ThuringiensisCRY1A Toxins,” Jul. 1999, Dissertation submitted to the Dept. of Molecular Biology and The Graduate School of the University of Wyoming.
Midboe, E.G., “Characterization of the BT-R1Gene and Its Expression inManduca Sexta,” Jul. 1999, Dissertation submitted to the Dept. of Molecular Biology and The Graduate School of the University of Wyoming.
Nagamatsu, Y., et al., “Cloning, Sequencing, and Expression of the Bombyx Mori Receptor forBacillus ThurigiensisInsecticidal CrylA(A) Toxin,”Biosci. Biotechnol. Biochem, 1998, vol. 62(4), pp. 727-734.
Nagamatsu, Y. et al., “The Cadherin-Like Protein is Essential to Specificity Determination and Cytotoxic Action of theBacillus ThuringiensisInsecticidal CrylAa Toxin,”Febs Letters, 1999, vol. 460, pp. 385-390.
Oddou, P., et al., “Immunologically Unrelated Heliothis Sp. And Spodoptera Sp. Midgut Membrane-Proteins BindBacillus ThuringiensisCrylA(b) δ-endotoxin,”Eur. J. Biochem., 1993, vol. 212, pp. 145-150.
Roush, R., et al., “Assessing the Odds: The Emergence of Resistance to BT Transgenic Plants,”Nature Biotechnology, 1997, vol. 15, pp. 816-817.
Skolnick, J. et al., “From Genes to Protein Structure and Function: Novel Applications of Computational Approaches in the Genomic Era,”Trends in Biotechnology, pp. 34-39, vol. 18, No. 1.
Vadlamudi, R., et al., “Cloning and Expression of a Receptor for an Insecticidal Toxin ofBacillus Thuringiensis,”The Journal of Biological Chemistry, 1995, vol. 270(10), pp. 5490-5494.
Vadlamudi, R., et al., “A Specific Binding Protein fromManduca Sextafor the Insecticidal Toxin ofBacillus ThuringiensisSubsp. Berliner,”The Journal of Biological Chemistry, 1993, vol. 268(17), pp. 12334-12340.
Rudinger, J., “Characteristics of the Amino Acids as Components of a Peptide Hormone Sequence,”J.A. Parsons University, 1976, Park Press, Baltimore, pp. 1-7.

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