Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal
Patent
1973-06-20
1976-07-13
Ford, John M.
Chemistry of carbon compounds
Miscellaneous organic carbon compounds
C-metal
424279, 424195, C07D31120
Patent
active
039693694
ABSTRACT:
There is provided a novel simaroubolide derived from Brucea antidysenterica which possesses high and surprising anti-leukemic activity at dosage levels of micrograms per kilogram body weight.
REFERENCES:
cancer Chemotherapy Reports, Part 3, vol. 3, No. 2, p. 9 (Protocol 1.200), Sept. 1972.
Drug Research and Development Instruction 14, Cancer Treatment, National Cancer Institute, Bethesda, MD.
Britton Ronald W.
Kupchan S. Morris
Ford John M.
Research Corporation
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