Broad spectrum vaccine against gonorrhea

Details Broad spectrum vaccine against gonorrhea Broad spectrum vaccine against gonorrhea

1985-07-25

1986-11-11

Hazel, Blondel

Drug, bio-affecting and body treating compositions

Whole live micro-organism, cell, or virus containing

Genetically modified micro-organism, cell, or virus

424 88, 530326, 530327, 530328, A61K 39095, C07K 706, C07K 708

Patent

active

046222235

ABSTRACT:
Vaccines comprising peptide sequences corresponding to immunorecessive determinants in gonorrhea pilus protein are disclosed. The vaccines are effective in protecting human subjects against infection by a wide range of gonorrhea strains by raising antibodies which interfere with the colonization of the epithelium by the infecting bacteria or which enhance phagocytosis.

REFERENCES:
patent: 4443431 (1984-04-01), Buchanan et al.
Chemical Abstracts, vol. 98, Abstract No. 213829n, 1983.
Chemical Abstracts, vol. 101, Abstract No. 125160n, 1984.

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