Broad spectrum influenza antisera

Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues – 25 or more amino acid residues in defined sequence

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530328, 530387, 530403, 424 88, 424 89, 424 86, 424 85, C07K 706, C07K 710, C07K 1702, A61K 39145

Patent

active

046250158

ABSTRACT:
Antisera against synthetic peptides which neutralize influenza viruses of differing hemagglutinin subtypes, provide protection against infection by influenza virus and methods of preparing the same are disclosed.

REFERENCES:
Muller, G. et al., Proc. Natl. Acad. Sci., vol. 79, pp. 569-573, 1982.
Green, N. et al., Cell, vol. 28, pp. 477-487, 1982.
Jackson, D. et al., Virology, vol. 120, pp. 273-276, 1982.
Min Jou, W. et al., Cell, vol. 19, pp. 683-696, 1980.
Arcus et al., Intervirology, 15, 145 (1981).
Lamb et al., Nature, 300, 66 (1982).
Wabuke-Bunoti et al., J. Immunol., 130, 2386 (1983).

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