Broad ion fragmentation coverage in mass spectrometry by...

Radiant energy – Ionic separation or analysis – Methods

Reexamination Certificate

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C250S281000, C250S299000, C250S300000, C250S42300F

Reexamination Certificate

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10425190

ABSTRACT:
In the field of mass spectrometry, a method of obtaining a mass spectrum enriched with fragment ions while retaining the precursor ion. The technique includes varying the collision energy experienced by the precursor ion such that a range of fragmentations occur. Related methods are also disclosed for obtaining MS, MS2, MS3and MSnspectra which are enriched with fragment ions.

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Haller et al., Collision Induced Decomposition of Peptides. Choice of Collision ParametersJ. Am. Soc. Mass Spectrum 1996, 7, 677-681.

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