Bridged macrocyclic module compositions

Details Bridged macrocyclic module compositions Bridged macrocyclic module compositions

2008-05-06

2008-05-06

Kumar, Shailendra (Department: 1621)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C525S327400, C525S329500, C205S751000

Reexamination Certificate

active

07368564

ABSTRACT:
This invention is related to the fields of organic chemistry and nanotechnology. In particular, it relates to materials and methods for the preparation of organic synthons and bridged macrocyclic module compounds. The bridged macrocyclic module compounds may be used to prepare macrocyclic compositions such as nanofilms, which may be useful for filtration.

REFERENCES:
Kwit et al, Tetrahedron: Asymmetry, vol. 14, pp. 1303-1308, 2003.
Korupoju et al, Inorganic Chemistry, vol. 41, No. 16, 2002, pp. 4099-4101.
Coope et al. “Predictive blood glucose lowering efficacy by glucokinase activators in high fat fed female Zucker rats” British Journal of Pharmacology 149:328-335 (2006).
Gill et al. “Stimulation of insulin release in MIN6 cells and isolated rodent islets by a small molecule glucokinase activator (GKA50)” poster presented at 42nd EASD Meeting Copenhagen (2006).
Gill et al. “Upregulation of key β-cell genes and improvement of function in rodent islets following chronic in vitro treatment with a glucokinase activator” poster presented at 43rd EASD Meeting, Amsterdam (Sep. 17-21, 2007).
Gorman et al. “Effect of high-fat diet on glucose homeostasis and gene expression in glucokinase (GK) Heterozygous Knock-Outs” Abstract No. 0108-OR, 67th Annual ADA Scientific Sessions (2007).
Johnson et al. “Glucose-dependent modulation of insulin secretion and intracellular calcium ions by GKA50 - A glucokinase activator” Abstract No. 0592-P, 67th Annual ADA Scientific Sessions (2007).
Leighton et al. “Improved glycemic control after sub-acute administration of a glucokinase activator to male zucker (fa/fa) rats” Abstract No. 0377-OR, 67th Annual ADA Scientific Sessions (2007).
McKerrecher et al. “Design and synthesis of novel glucokinase activators as potention treatments for type 2 diabetes” 233rd National Meeting and Exposition, Chicago, IL (Mar. 25-29, 2007).
McKerrecher et al. “Identification of orally bioavailable small molecule activators of glucokinase” Abstract, 12thSCI-RSC Medicinal Chemistry Symposium, Cambridge, UK, Sep. 7-10, 2003 (poster 21) and 227thAmerican Chemical Society National Meeting and Exposition, San Francisco, California, Mar. 28-Apr. 1, 2004 (paper 341).
Winzell et al. “Glucokinase activation reduces glycemia and improves glucose tolerance in mice with high-fat diet-induced insulin resistance” Abstract No. 1482-P, 67th Annual Scientific Sessions (2007).
RAJCA et al., “Biphenylene dimer. Molecular fragmant of a two-dimensional carbon net and double-stranded polymer,”J. Am. Chem. Soc.,118:7272-7279 (1996).
Kanamathareddy et al., “Conformational characteristics ofp-tert-Butylcalix[6]arene ethers,”J. Org. Chem.,59:3871-3879 (1994).
Hendel et al., “Assembly and Disassembly of Langmuir-Blodgett Films on Poly[1-(trimethylsilyl)-1-propyne]: The Uniqueness of Calix[6]arene Multilayers as Permeation-Selective Membranes,”J. Am. Chem. Soc.,119:6909-6918 (1997).

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