Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2005-08-30
2005-08-30
Kifle, Bruck (Department: 1624)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
C514S220000, C540S555000, C540S556000, C540S058000, C540S559000
Reexamination Certificate
active
06936604
ABSTRACT:
The invention is directed to bridged bicyclic amino acid-derived [1,4]benzodiazepine compounds, intermediates and pharmaceutical compositions thereof useful as vasopressin receptor antagonists and methods for treating vasopressin mediated disorders.
REFERENCES:
patent: 3860600 (1975-01-01), Carabateas
patent: 5258510 (1993-11-01), Ogawa et al.
patent: 5521173 (1996-05-01), Venkatesan et al.
patent: 5559230 (1996-09-01), Ogawa et al.
patent: 5700796 (1997-12-01), Albright et al.
patent: 5985869 (1999-11-01), Ogawa et al.
patent: 6713475 (2004-03-01), Hoekstra et al.
patent: 0 987 266 (2000-03-01), None
patent: WO 00 43398 (2000-07-01), None
Trybulski; Annual Reports in Medicinal Chemistry-36, Chapter 16 “Vasopressin Receptor Modulators: From Non-peptide Antagonists to Agonists” (2001).
PCT International Search Report PCT/US02/32789 dated Jan. 9, 2003.
Ohtake, Y. et al; “Novel Vasopressin V2 Receptor-selective Antagonists, Pyrrolo[2,1-a]quinoxaline and Pyrrolo[2,1-c][1,4]benzodiazepine Derivatives”; Bioorganic & Medicinal Chemistry, 1999; pp. 1247-1254; vol. 7, No. 6; Elsevier Science Ltd.; XP002225041.
Dyatkin, Alexey B., et al., “Bridged Bicyclic Vasopressin Receptor Antagonists with V2-Selective or Dual V1a/V2Activity”, Bioorganic & Medicinal Chemistry Letters, vol. 12, Issue 21, Nov. 4, 2002, pp 3081-3084.
Van Zwieten, P.A., Progr. Pharmacol. Clin. Pharmacol. 1990, 7, 49-66.
Ogawa, H., J. Med. Chem. 1996, 39, 3547-3555.
Fujisawa, G., Kidney Int. 1993, 44(1), 19-23.
Ref. International J. Pharm., 1986, 33, 201-217.
J. Pharm. Sci., 1997 (Jan), 86, 1, 1-12.
Hamley et al., in Synlett, 1991,29-30.
Bailey, P.D., et al., Tetrahedron: Asymmetry, 1991, 2(12), 1263-1282.
Bailey, P.D., et al., Tetrahedron Letters, 1989, 30(48), 6781-6784.
Campbell, J.A., et al., J. Org. Chem. 1996, 61, 6313-6325.
Dyatkin Alexey B.
Hoekstra William J.
Maryanoff Bruce E.
Kifle Bruck
Lopez Gabriel
Ortho-McNeil Pharmaceutical , Inc.
Woodrow Hal B.
LandOfFree
Bridged bicyclic amino acid-derived [1,4]benzodiazepine... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Bridged bicyclic amino acid-derived [1,4]benzodiazepine..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Bridged bicyclic amino acid-derived [1,4]benzodiazepine... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3503503