Drug – bio-affecting and body treating compositions – Dentifrices
Patent
1995-05-11
1997-12-16
Azpuru, Carlos A.
Drug, bio-affecting and body treating compositions
Dentifrices
424 48, 424441, 424444, A61K 716, A61K 968, C01B 3132, C01B 3126
Patent
active
056981813
ABSTRACT:
The present invention is a directed at chewing gum compositions having long-lasting breath freshening perception without bitterness comprising (a) a gum base; (b) a bulking agent; and (c) a cooling composition; wherein the cooling composition comprises menthol and an N-substituted-p-menthane carboxamide, wherein the carboxamide may be represented by the formula: ##STR1## wherein R.sub.1 and R.sub.2 may be independently selected from the group consisting of hydrogen and an alkyl group containing from 1 to 25 carbon atoms, with the proviso that when R.sub.1 is hydrogen, R.sub.2 may be an aryl group containing from 6 to 10 carbon atoms and, R.sub.1 and R.sub.2 when taken together, may be a cyclic or heterocyclic group containing up to 25 carbon atoms; and wherein the N-substituted-p-menthane carboxamide is present in the cooling composition in an amount from about 0.001% to about 6%, and menthol is present in the cooling composition in an amount from about 94% to about 99.999%. The present invention is also directed at confectionery compositions containing the novel cooling composition and methods for preparing the novel chewing gum and confectionery compositions.
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Azpuru Carlos A.
Vag Linda A.
Warner-Lambert & Company
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