Surgery – Respiratory method or device – Means for mixing treating agent with respiratory gas
Patent
1981-06-29
1984-05-08
Padgett, Benjamin R.
Surgery
Respiratory method or device
Means for mixing treating agent with respiratory gas
A61M 1506
Patent
active
044468628
DESCRIPTION:
BRIEF SUMMARY
This invention relates to a device for administering powdered medicaments by oral inhalation and which is actuated by the inhalation of the patient.
There are many devices for administering powdered medicaments to the alveolar region of the lungs which employ propellants, such as compressed gases, e.g. air, or liquefied gas propellants, to dispense and disperse the medicament. These devices tend to be complex to construct and have the disadvantage that in order for the optimum effect to be obtained it is essential that inhalation and dispensing be synchronous.
There are also a number of known breath actuated inhalation devices for administering powdered medicaments to the lungs which have mouthpieces through which the medicament is inhaled. The powdered medicament is usually supplied in capsules which are substantially cylindrical in shape and have rounded ends. The capsule is formed in two halves having different diameters, one half being a push-fit within the other. In the simpler breath actuated devices the capsule is opened prior to insertion into the device and one half of the capsule containing the medicament or the medicament itself is positioned in the device such that during inhalation through the mouthpiece the medicament becomes entrained in the air stream and passes to the patient. Examples of such devices are disclosed in British Patent Specification Nos. 1 520 064, 1 504 441, 1 118 341, 1 520 063 and 1 520 062. These devices suffer from the disadvantage that medicament may be spilled when the capsule is opened prior to insertion in the device.
British Patent Specification Nos. 1 521 000, 1 520 062, 1 472 650 and 1 502 150 disclose more complex devices in which the complete capsule is inserted into the device thus ensuring no spillage of medicament prior to inhalation, and access to the medicament is gained by piercing the capsule or cutting it in half, inside the dispensing device. On inhalation the air flows into or through the capsule and the powder within is released into the air stream and flows towards the mouth.
The devices disclosed in British Patent Specification Nos. 1 485 163, 1 331 216, 1 457 352, 1 396 258, 1 182 779, 1 404 338, 1 459 426 and 1 118 431 and U.S. Patent Specification Nos. 4 117 844 and 4 116 195 are designed to agitate the capsule containing the medicament in order to help release and disperse the powder from the capsule. The capsule may be agitated by various means, e.g. creating a turbulent air flow, or by rotational and/or vibrational motion of the capsule with the use of vanes or propellors. These devices incorporate complex arrangements and are often difficult to operate.
U.S. Patent Specification No. 4 210 140 discloses a device in which access to the powdered medicament is gained by pulling the halves of the capsule apart so that the medicament is emptied to a suitable position for entrainment in the air flow caused by inhalation.
In spite of the numerous prior art devices there is a need for a breath actuated device which is simple to operate and efficient in administering powdered medicaments into the alveolar region of the lungs.
The present invention provides a breath actuated device for the oral inhalation of medicaments in finely divided powder form, comprising a chamber having one or more inlet ports for the entry of air and an outlet in direct communication with a mouthpiece and, positioned within the chamber, means for separating the lid and base components of a capsule (as defined herein) containing the medicament whilst holding the capsule substantially vertically to expose an aperture in the base component facilitating access to the powdered medicament and means for supporting the base component of the capsule containing the powdered medicament in a substantially vertical position, the inlet ports, outlet port and means for supporting the base component of the capsule being arranged such that when the device is operated by suction at the mouthpiece an air flow is established from the inlet ports to the outlet port directly across the aperture in t
REFERENCES:
patent: 3906950 (1975-09-01), Cocozza
patent: 4116195 (1978-09-01), James
patent: 4192309 (1980-03-01), Poulsen
patent: 4206758 (1980-06-01), Hallworth et al.
patent: 4210140 (1980-07-01), James et al.
Baum Eric A.
Davies Leslie J.
Kirk William F.
Wass Anthony C. L.
Huebsch William L.
Padgett Benjamin R.
Sell Donald M.
Smith James A.
Wallen T. J.
LandOfFree
Breath actuated devices for administering powdered medicaments does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Breath actuated devices for administering powdered medicaments, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Breath actuated devices for administering powdered medicaments will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1597312