Breast cyst fluid protein assay

Chemistry: analytical and immunological testing – Involving immune complex formed in liquid phase – Separation of immune complex from unbound antigen or antibody

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436542, 436543, 436544, 436545, 436804, 436813, 436811, 260112R, 260112B, 2601125R, G01N 3354, G01N 3358, G01N 3360, C07C 700

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044408633

ABSTRACT:
This disclosure relates to assay of a glycoprotein component of human breast gross cystic disease fluid which has been designated GCDFP-15. This material is a useful marker in monitoring the efficacy of therapy in women with metastatic breast carcinoma and also in determining the maturity of the fetus in pregnant women. The assay for GCDEP-15 can also be used in conjunction with other assays for breast carcinoma such as an assay for carcinoembryonic antigen (CEA) whereby the utilization of both tests is more effective in monitoring for recurrence of disease than using either assay alone.

REFERENCES:
patent: 4229426 (1980-10-01), Haagensen, Jr.
Haagensen, Jr. et al., Annals of Surgery, 185(3), 279-285 (1977).
Haagensen, Jr. et al., J. Natl. Cancer Inst., 62(2), 239-247 (1979).

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