Breast cancer resistance protein (BCRP) and antibodies thereto

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues

Reexamination Certificate

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Reexamination Certificate

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07465788

ABSTRACT:
The present invention provides a breast cancer resistance polynucleotide and protein ofMacaca mulata(rhesus monkey) and uses thereof. The present invention also provides anti-BCRP antibodies and uses thereof, particularly as a hematopoietic stem cell marker.

REFERENCES:
Mikayama et al. PNAS, 1993. 90: 10056-10060.
Burgess et al J Cell Biol. 111:2129-2138, 1990.
Wang et al. JBC, 2001 276:49213-49220.
Bowie et al. Science, 247:1306-1310, 1990.
Metzler et al. Nature Structural Biol. 1997; 4:527-531.

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